Mapping and expression analysis of the human CASK gene

Mapping and expression analysis of the human CASK gene Mammalian Genome 11, 934–937 (2000). DOI: 10.1007/s003350010170 Incorporating Mouse Genome © Springer-Verlag New York Inc. 2000 David Stevenson, Hugh G. Laverty,* Sandra Wenwieser, Morag Douglas, Joanna B. Wilson Robertson Laboratory, Division of Molecular Genetics, Institute of Biomedical and Life Sciences, University of Glasgow, 54 Dumbarton Road, Glasgow G11 6NU, UK Received: 24 January 2000 / Accepted: 24 May 2000 Cleft palate is a common disease of humans, occurring in 1 in 2000 sen as representative of each and sequenced. (Genbank accession live births with heritable and sporadic forms. The complex bio- numbers are AF262404 and AF262405 respectively). Analysis of logical events required for palate formation in the human embryo both hCASK sequences indicated tremendous similarity to rodent mean that disruption of various developmental steps may result in CASK; however, both clones carried completely distinct (from clefting (Ferguson 1987). Consequently, acquiring sufficient data each other and rCASK) 58 sequences juxtaposed to the CASK to identify genetic loci involved in cleft palate formation has sequences (Fig. 1C). BLAST database searching revealed similar- proven difficult. However, study of X-linked cases found in rela- ity between the 58 end of f7 and human Chr 5 pac clone 117n3 tively inbred kindreds (Moore et http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Mapping and expression analysis of the human CASK gene

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Publisher
Springer-Verlag
Copyright
Copyright © 2000 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003350010170
Publisher site
See Article on Publisher Site

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