Curr Hepatology Rep (2017) 16:169–177 DOI 10.1007/s11901-017-0352-z HEPATITIS B (J LIM, SECTION EDITOR) Management and Treatment of Chronic HBV and HCV Co-Infection and the Impact of Anti-Viral Therapy 1 2 Mitchell L. Shiffman & Nadege T. Gunn Published online: 19 July 2017 Springer Science+Business Media, LLC 2017 . . Abstract Keywords Hepatitis B virus Hepatitis C virus . . Purpose of Review Recent reports have demonstrated that Co-infection Direct-acting anti-viral agents Peginterferon chronic hepatitis B virus (HBV) can flare or reactivate when alpha Ribavarin chronic hepatitis C virus (HCV) is treated with direct-acting anti-viral agents (DAAs). Understanding HBV and HCV co- infection is therefore important. Epidemiology Recent Findings Although 40–60% of patients with chronic HCV have been previously exposed to HBV; only about 1– Chronic viral hepatitis B (HBV) and C (HCV) collectively 6% has serologic evidence of co-infection. In some patients represent the most common cause of chronic liver disease with co-infection, both HBsurface antigen and HBV DNA worldwide. An estimated 350 million persons have chronic may be suppressed to undetectable levels by HCV. Complete HBV . The areas of the world with the highest prevalence serologic screening for HBV should be performed in all pa- for HBV
Current Hepatology Reports – Springer Journals
Published: Jul 19, 2017
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