Lymphatic mapping and sentinel node biopsies: not just for melanoma!

Lymphatic mapping and sentinel node biopsies: not just for melanoma! Eur J Plast Surg (2001) 24:150–151 DOI 10.1007/s002380100255 INVITED COMMENTAR Y Alistair J. Cochran Published online: 9 May 2001 © Springer-Verlag 2001 The techniques of lymphatic mapping and sentinel node tional [8] and in situ [9] forms can supplement data from biopsy [1] were developed to provide a more rational ap- more conventional pathologic evaluation. proach to the management of patients with high-risk The techniques of lymphatic mapping for melanoma (thick, deep) primary melanomas and clinically negative are thus well established. It is widely accepted that this regional nodes. Required are the capacity to identify the method is the best available approach to clinical staging first lymph node(s) on the direct lymphatic drainage path and that, in the presence of even single melanoma cells from the primary tumor (the sentinel node or nodes) [2] in the sentinel node, a completion lymphadenectomy and the ability to detect accurately even very small num- should be undertaken. The therapeutic role of these ap- bers of tumor cells in these nodes [3]. proaches will become known when outcome data from Identification of the sentinel nodes requires “early ongoing trials become available in a year or so. read” or “dynamic” lymphoscintigraphy [4, 5], in European Journal of Plastic Surgery Springer Journals

Lymphatic mapping and sentinel node biopsies: not just for melanoma!

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Copyright © 2001 by Springer-Verlag
Medicine & Public Health; Plastic Surgery
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  • Occult melanoma in lymph nodes detected by antiserum to S-100 protein
    Cochran, AJ; Wen, D-R; Herschman, JR
  • Sentinel node biopsy in melanoma patients: dynamic lymphoscintigraphy followed by intraoperative gamma probe and vital dye guidance
    Pijpers, R; Borgstein, PJ; Meijer, S

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