Longitudinal Effects of Syndemics on ART Non-adherence Among Sexual Minority Men

Longitudinal Effects of Syndemics on ART Non-adherence Among Sexual Minority Men This study examined longitudinally the additive effect of syndemics, or co-occurring psychosocial problems, on antiretroviral treatment (ART) non-adherence among 390 HIV-positive sexual minority men. Participants completed measures of ART adherence (reduced to a non-adherence score using exploratory factor analysis) and six syndemic conditions. We employed multilevel modeling with the number of syndemics as a longitudinal predictor of non-adherence, and logistic regression with baseline syndemics predicting follow up viral load. Number of syndemics was a significant longitudinal predictor of non-adherence, with each additional syndemic associated with a 0.13 increase in non-adherence (p = 0.004). Each additional syndemic was also associated with 1.27 greater odds of detectable viral load (p = 0.002). Among HIV-positive sexual minority men in this sample, more syndemics were associated with lower ART adherence and greater odds of detectable viral load, suggesting the need for behavioral intervention to facilitate care for this population. Keywords HIV · Sexual minority · Syndemics · Antiretroviral therapy/ART  · Adherence Resumen Este estudio examinó longitudinalmente el efecto aditivo de sindémicas, o problemas psicosociales concurrentes, sobre la falta de adherencia al tratamiento antirretroviral (ART por sus siglas en inglés) entre 390 hombres VIH positivos de mino- rías sexuales. Los participantes completaron medidas de adherencia al ART (reducidas a http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AIDS and Behavior Springer Journals

Longitudinal Effects of Syndemics on ART Non-adherence Among Sexual Minority Men

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Publisher
Springer US
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Public Health; Health Psychology; Infectious Diseases
ISSN
1090-7165
eISSN
1573-3254
D.O.I.
10.1007/s10461-018-2180-8
Publisher site
See Article on Publisher Site

Abstract

This study examined longitudinally the additive effect of syndemics, or co-occurring psychosocial problems, on antiretroviral treatment (ART) non-adherence among 390 HIV-positive sexual minority men. Participants completed measures of ART adherence (reduced to a non-adherence score using exploratory factor analysis) and six syndemic conditions. We employed multilevel modeling with the number of syndemics as a longitudinal predictor of non-adherence, and logistic regression with baseline syndemics predicting follow up viral load. Number of syndemics was a significant longitudinal predictor of non-adherence, with each additional syndemic associated with a 0.13 increase in non-adherence (p = 0.004). Each additional syndemic was also associated with 1.27 greater odds of detectable viral load (p = 0.002). Among HIV-positive sexual minority men in this sample, more syndemics were associated with lower ART adherence and greater odds of detectable viral load, suggesting the need for behavioral intervention to facilitate care for this population. Keywords HIV · Sexual minority · Syndemics · Antiretroviral therapy/ART  · Adherence Resumen Este estudio examinó longitudinalmente el efecto aditivo de sindémicas, o problemas psicosociales concurrentes, sobre la falta de adherencia al tratamiento antirretroviral (ART por sus siglas en inglés) entre 390 hombres VIH positivos de mino- rías sexuales. Los participantes completaron medidas de adherencia al ART (reducidas a

Journal

AIDS and BehaviorSpringer Journals

Published: Jun 2, 2018

References

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