Localization of Zap70, the gene for a T cell-specific protein tyrosine kinase, to mouse and rat chromosomes by fluorescence in situ hybridization and molecular genetic linkage analyses

Localization of Zap70, the gene for a T cell-specific protein tyrosine kinase, to mouse and rat... Mammalian Genome 8, 45--46 (1997). e//o///e 9 Springer-Verlag New York Inc. 1997 Localization of Zap70, the gene for a T cell-specific protein tyrosine kinase, to mouse and rat chromosomes by fluorescence in situ hybridization and molecular genetic linkage analyses T. Saito, 1 Y. Matsuda, 1 H. Ito, 1 N. Fusaki, z T. Hori, 1 T. Yamamoto 2 1Division of Genetics, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263, Japan 2Department of Oncology, Institute of Medical Science, Tokyo University, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108, Japan Received: 1 September 1995 / Accepted: 23 August 1996 Zap70, the gene for a non-SRC type protein tyrosine kinase that ease (Arpaia et al. 1994; Chan et al. 1994; Elder et al. 1994). These has recently been demonstrated to play an essential role in T cell studies indicated that absence of the ZAP70 protein results in an development and function, was mapped to mouse Chromosome inability to mediate the signals of T cell receptor and produces a (Chr) 1B and rat Chr 9q22.1 by direct R-banding fluorescence in distinctive form of human severe combined immunodeficiency. situ hybridization (FISH). The gene was localized also by genetic Although detailed basic biochemical studies on the mechanism http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Localization of Zap70, the gene for a T cell-specific protein tyrosine kinase, to mouse and rat chromosomes by fluorescence in situ hybridization and molecular genetic linkage analyses

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Publisher
Springer-Verlag
Copyright
Copyright © 1997 by Springer-Verlag
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900345
Publisher site
See Article on Publisher Site

Abstract

Mammalian Genome 8, 45--46 (1997). e//o///e 9 Springer-Verlag New York Inc. 1997 Localization of Zap70, the gene for a T cell-specific protein tyrosine kinase, to mouse and rat chromosomes by fluorescence in situ hybridization and molecular genetic linkage analyses T. Saito, 1 Y. Matsuda, 1 H. Ito, 1 N. Fusaki, z T. Hori, 1 T. Yamamoto 2 1Division of Genetics, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263, Japan 2Department of Oncology, Institute of Medical Science, Tokyo University, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108, Japan Received: 1 September 1995 / Accepted: 23 August 1996 Zap70, the gene for a non-SRC type protein tyrosine kinase that ease (Arpaia et al. 1994; Chan et al. 1994; Elder et al. 1994). These has recently been demonstrated to play an essential role in T cell studies indicated that absence of the ZAP70 protein results in an development and function, was mapped to mouse Chromosome inability to mediate the signals of T cell receptor and produces a (Chr) 1B and rat Chr 9q22.1 by direct R-banding fluorescence in distinctive form of human severe combined immunodeficiency. situ hybridization (FISH). The gene was localized also by genetic Although detailed basic biochemical studies on the mechanism

Journal

Mammalian GenomeSpringer Journals

Published: Mar 23, 2009

References

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