Brief Data Reports 9 ~rellome Mammalian Genome 8, 941-952 (1997). 9 Springer-Verlag New York Inc. 1997 Discussion: Tyrosine kinase 10 (Tyro 10) is a receptor protein Localization of the mouse gene encoding tyrosine kinase (RTK) that was first identified in a PCR-based tyrosine kinase receptor type 10 on distal survey of RTKs expressed in the rat nervous system . As well Chromosome 1 as being expressed in the brain, it is also expressed in the kidney, skeletal muscle, and heart muscle of adult mice, and at lower levels in the liver and stomach. Embryonically, it is expressed in the Jennifer N. Murdoch, 1 Jane Eddleston, 2 developing nervous system, abundantly at embryonic day 12 (in Philip Stanier, 2 Andrew J. Copp 1 rats), but in decreasing amounts as development proceeds . The function of TyrolO is unknown, but RTKs play a critical 1Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK role in signal transduction in a number of processes, including cell 2Institute of Obstetrics and Gynaecology, Queen Charlotte's and Chelsea growth and differentiation. TyrolO belongs to an unusual subclass Hospital, Goldhawk Road, London W6 0XG, UK of RTKs, since it
Mammalian Genome – Springer Journals
Published: Mar 21, 2009
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