Localization of rat genes in the nitric oxide signaling pathway: candidates for the pathogenesis of complex diseases

Localization of rat genes in the nitric oxide signaling pathway: candidates for the pathogenesis... Mammalian Genome 10, 71–73 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 Localization of rat genes in the nitric oxide signaling pathway: candidates for the pathogenesis of complex diseases 1,2 1 2 1 3 1,2 George Koike, Jean-Daniel Chiche, Masahide Shiozawa, Jason S. Simon, Josiane Szpirer, Howard J. Jacob, 3 1 Claude Szpirer, Kenneth D. Bloch The Cardiovascular Research Center, Massachusetts General Hospital-East, 149 13th Street, Charlestown, Massachusetts 02129-2060, USA The Medical College of Wisconsin, Department of Physiology, 8701 Watertown Plank Road, P.O. Box 26509, Milwaukee, Wisconsin 53226-0509, USA De ´partement de Biologie Mole ´culaire, Universite ´ Libre de Bruxelles, B-1640 Rhode-St-Gene `se, Belgium Received: 4 August 1998 / Accepted: 28 August 1998 Nitric oxide (NO) has critical regulatory function in multiple cell mic fragments containing these genes. A cDNA for PRKGI was types. In the vasculature, NO is a vasodilator but also modulates generated by reverse transcription followed by polymerase chain smooth muscle cell proliferation (Schmidt and Walter 1994) and reaction (RT-PCR) from rat brain mRNA with degenerate primers apoptosis (Pollman et al. 1996). In the nervous system, NO serves (forward primer: 58-CCGAATTCAGGAGCATGGGCACCYT- as a neurotransmitter, whereas, in endocrine tissues, NO has im- GCG-38; reverse primer: http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Localization of rat genes in the nitric oxide signaling pathway: candidates for the pathogenesis of complex diseases

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Publisher
Springer-Verlag
Copyright
Copyright © 1999 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900946
Publisher site
See Article on Publisher Site

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