Reactions 1680, p204 - 2 Dec 2017
Anxiety with recurrence and aggravation of night
terror: case report
A 23-year-old man experienced anxiety with recurrence and
aggravation of night terror during treatment with
lisdexamfetamine [route, dosage and indication not stated].
The man, who had a history of childhood night terrors,
reported recurrence of night terror just a month after the
initiation of lisdexamfetamine therapy. During childhood, he
used to had night terrors at an interval of three to four times
per year, whereas currently he was experiencing recurrence
three to five times per week. At presentation, he had a BP of
140/96 and a pulse of 105 [units not stated]. His mental status
examination showed anxious mood with congruent affect. On
anamnesis, he reported night terror as a black figure appearing
next to the door or the bed. At that time, he was unable to
speak or to move. Then, he shouted loudly. Thereafter, his
parents woke him up from terror sleep [outcomes not stated].
Author comment: "Possibly, [lisdexamfetamine] acted to
precipitate night terrors by functioning as a dopamine
receptor agonist." "Lisdexamfetamine may be inducing night
terror indirectly through enhancement of anxiety."
Makwana MN, et al. The incubus strikes again: Recurrence of sleep terrors with
lisdexamfetamine administration. CNS Spectrums 22: 84-85 (plus poster) abstr.
140, No. 1, 7 Feb 2017. Available from: URL: http://doi.org/10.1017/
S1092852916000900 [abstract] - India
Reactions 2 Dec 2017 No. 16800114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved