Lisdexamfetamine Reactions 1680, p204 - 2 Dec 2017 Anxiety with recurrence and aggravation of night terror: case report A 23-year-old man experienced anxiety with recurrence and aggravation of night terror during treatment with lisdexamfetamine [route, dosage and indication not stated]. The man, who had a history of childhood night terrors, reported recurrence of night terror just a month after the initiation of lisdexamfetamine therapy. During childhood, he used to had night terrors at an interval of three to four times per year, whereas currently he was experiencing recurrence three to five times per week. At presentation, he had a BP of 140/96 and a pulse of 105 [units not stated]. His mental status examination showed anxious mood with congruent affect. On anamnesis, he reported night terror as a black figure appearing next to the door or the bed. At that time, he was unable to speak or to move. Then, he shouted loudly. Thereafter, his parents woke him up from terror sleep [outcomes not stated]. Author comment: "Possibly, [lisdexamfetamine] acted to precipitate night terrors by functioning as a dopamine receptor agonist." "Lisdexamfetamine may be inducing night terror indirectly through enhancement of anxiety." Makwana MN, et al. The incubus strikes again: Recurrence of sleep terrors with lisdexamfetamine administration. CNS Spectrums 22: 84-85 (plus poster) abstr. 140, No. 1, 7 Feb 2017. Available from: URL: S1092852916000900 [abstract] - India 803284805 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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