Linkage mapping of Sax2 to mouse Chromosome 5

Linkage mapping of Sax2 to mouse Chromosome 5 Brief Data Reports Mammalian Genome 8, 697-708 (1997). 9 Springer-Verlag New York Inc. 1997 to the murine Saxl gene [6], which also has 95% amino acid Linkage mapping of Sax2 to mouse identity relative to NK1/$59, which in turn is slightly greater than Chromosome 5 the chicken homolog Saxl/CHox3 [7], which shares only 93% amino acid identity with NK1/S59 (Fig. 1B). The NK1/S59 family Xiaowei Chen, Thomas Lufkin falls into the much larger NK-super family that has over twenty members [8], which makes it the second biggest homeobox gene Brookdale Center for Developmental and Molecular Biology, Mount family, after the Hox gene family [9]. Sinai School of Medicine, Box 1126, One Gustave L. Levy Place, In Drosophila, the NK1/$59 gene is expressed in muscle pre- New York, New York 10029-6574, USA cursor cells during embryogenesis. Around 2 hours postgastrula- tion, NK1/$59 expression appears in several groups of segmentally Received: 3 April 1997 / Accepted: 8 May 1997 repeated mesodermal cells. With time, this expression evolves into four groups of founder mesodermal cells located within each ab- Species: Mouse dominal hemisegment, which after fusion with adjacent myoblasts Locus name: Sax homeobox gene 2 give rise to distinct somatic muscles [4]. Mammalian Genome Springer Journals

Linkage mapping of Sax2 to mouse Chromosome 5

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Copyright © 1997 by Springer-Verlag
Life Sciences; Cell Biology; Anatomy; Zoology
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