Ninety-one new rat microsatellite chromosome markers were generated through screening chromosome-sorted DNA libraries. Of the 91 markers, 29 have been mapped to various rat chromosomes. Because of a lack of suitable polymorphisms among the appropriate rat strains of our interest, the remaining 62 markers are still unassigned, but are likely to be useful for geno-typing different rat strains employed to study a wide range of genetic traits other than blood pressure. With these new markers, two genes, encoding α2 adrenergic receptor, class II and gastric H,K-ATPase beta subunit, were mapped to regions on rat Chromosomes (Chrs) 1 and 16 respectively.
Mammalian Genome – Springer Journals
Published: Mar 28, 2009
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