Linkage mapping of rat chromosome markers generated from chromosome-sorted DNA

Linkage mapping of rat chromosome markers generated from chromosome-sorted DNA Ninety-one new rat microsatellite chromosome markers were generated through screening chromosome-sorted DNA libraries. Of the 91 markers, 29 have been mapped to various rat chromosomes. Because of a lack of suitable polymorphisms among the appropriate rat strains of our interest, the remaining 62 markers are still unassigned, but are likely to be useful for geno-typing different rat strains employed to study a wide range of genetic traits other than blood pressure. With these new markers, two genes, encoding α2 adrenergic receptor, class II and gastric H,K-ATPase beta subunit, were mapped to regions on rat Chromosomes (Chrs) 1 and 16 respectively. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Linkage mapping of rat chromosome markers generated from chromosome-sorted DNA

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Publisher
Springer-Verlag
Copyright
Copyright © 1998 by Springer-Verlag New York Inc
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900676
Publisher site
See Article on Publisher Site

Abstract

Ninety-one new rat microsatellite chromosome markers were generated through screening chromosome-sorted DNA libraries. Of the 91 markers, 29 have been mapped to various rat chromosomes. Because of a lack of suitable polymorphisms among the appropriate rat strains of our interest, the remaining 62 markers are still unassigned, but are likely to be useful for geno-typing different rat strains employed to study a wide range of genetic traits other than blood pressure. With these new markers, two genes, encoding α2 adrenergic receptor, class II and gastric H,K-ATPase beta subunit, were mapped to regions on rat Chromosomes (Chrs) 1 and 16 respectively.

Journal

Mammalian GenomeSpringer Journals

Published: Mar 28, 2009

References

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