Linkage mapping of Emx2 to mouse Chromosome 19

Linkage mapping of Emx2 to mouse Chromosome 19 Mammalian Genome 8, Brief Data Reports 71 BSS chromosome 19 defects lie close to the map position of Pkcq on Chr 2 determined here. D19BirT 9 9 [] [] [] [] [] S On the latest Chromosome Committee report for mouse Chr 2 2.13-+1.49 IB Ins l B D D [] D D (Mouse Genome Database, MGD), ltih2 is assigned together with 2.13 _+ 1.49 D19Mit1 9 [] 9 [] [] [] D2Mitl at 1 cM from the centromere. In human, ITIH2 (the ho- 4.25 _+ 2.08 Z=21.1 Emx2 9 [] 9 9 [] [] molog of mouse ltih2) maps to human 10p15, the same cytogenetic 1.05 _+ 1.06 Z=25.9 Xmv18 9 [] 9 9 9 [] band to which PKRCQ has been mapped [4]. Just distal to ltih2 there is another group of markers on mouse Chr 2 with homologs on human 10p including Mrcl, Vim, Bmil, and Gad2 (see Mouse Chromosome 2 Committee report at MGD). It appears that Pkcq is a further addition to this conserved segment of genes between mouse proximal Chr 2 and human 10p (see Fig. 1). D19Mit87 D19Xrf127 D19Mit5 D19Mit63 Pltr4 Htr7 References #PDE6CA5 1. Breen, M., Deakin, L., Macdonald, B., Miller, Mammalian Genome Springer Journals

Linkage mapping of Emx2 to mouse Chromosome 19

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Copyright © 1997 by Springer-Verlag
Life Sciences; Cell Biology; Anatomy; Zoology
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