Reactions 1704, p224 - 2 Jun 2018 Dyskinesias: 14 case reports In a study, 14 patients [ages and sexes not stated] developed dyskinesias during treatment with levodopa for Parkinson’s disease [dosages, routes and durations of treatments to reactions onsets not stated]. The patients were diagnosed with Parkinson’s disease and started receiving levodopa. Subsequently, the patients developed drug-induced dyskinesias (DID). Total duration of the DID was reported as 10 17 hours. The patients subsequently underwent a postero-ventral pallidotomy (PVP). An improvement in the dyskinesias was reported post-operatively. The daily dose of levodopa was reduced by 15% after the surgery, in 50% of the patients. However, the levodopa dose returned to the preoperative values six months after the surgery. Following six months of the surgery, the DID was found to be improved to 2 8 hours. Author comment: Lengthy pharmacotherapy of Parkinson’s disease (PD) leads already after 3 5 years of taking levodopa to the development of side effects in the form of various motor fluctuations and drug-induced dyskinesias (DID), which become an independent desadaptative factor that impacts the patient’s daily life activities. In our study, drug-induced dyskinesias after a unilateral PVP regressed on average by 68.3 ± 9.7% contraleterally and by 50% ipsilaterally. Tyurnikov VM, et al. Unilateral posteroventral pallidotomy in the treatment of drug-induced dyskinesia in Parkinson’s disease. Zhurnal Voprosy Neirokhirurgii Imeni N. N. Burdenko 81: 69-75, No. 5, 2017. Available from: URL: http:// doi.org/10.17116/neiro201781569-74 [Russian; summarised from a translation] - Russia 803322710 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704
Reactions Weekly – Springer Journals
Published: Jun 2, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera