Reactions 1680, p202 - 2 Dec 2017 Suicidal ideation and increased irritability: 2 case reports In a case series, a 79-year-old man developed suicidal ideation and increased irritability during treatment with primidone, and a 76-year-old woman developed suicidal ideation during treatment with levetiracetam and phenytoin [routes and dosages not stated]. Case 1: A 79-year-old man was admitted following a serious suicide attempt. He reported taking 30 pills of an unspecified drug starting with "p" [complete name of the drug not stated]. However, as nothing happened, he attempted suicide by cutting his wrist twice with a knife. His brother found him half- an-hour following the event. Four days prior to the admission, he was started on a treatment with primidone for tremor. He reported feeling increasingly irritable for the past two days. On admission, his primidone therapy was discontinued. He continued to feel non-suicidal with a broad affect. Case 2: A 76-year-old woman, who had a long history of epilepsy, was admitted following a suicide attempt by cutting her both wrists deeply. The cuts were deep and required tendon repair. She reported that she felt "it was the right thing to do" at the moment, and also felt acutely depressed after reading about her medication list and the list of their side effects. Her son-in-law found her four hours following the attempt. One day prior to the admission, she was started on a treatment with levetiracetam. Prior to that, she was on phenytoin therapy for over 30 years to treat epilepsy. One the day following the event, she had a complete resolution of suicidal ideation, and reported having a better mood. Author comment: "Here we present two cases of suicidality and their correlation with [antiepileptic drugs]." Gulwadi A, et al. Case series demonstrating risk of suicidality with antiepileptic drugs-suicide attempt after 4 days of primidone and 1 day of levetiracetam use. CNS Spectrums 21: 120, No. 1, Feb 2016. Available from: URL: http:// doi.org/10.1017/S1092852915000905 [abstract] - USA 803284797 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680
Reactions Weekly – Springer Journals
Published: Dec 2, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera