1062-3604/04/3506- © 2004
Russian Journal of Developmental Biology, Vol. 35, No. 6, 2004, pp. 394–395. Translated from Ontogenez, Vol. 35, No. 6, 2004, pp. 479–480.
Original Russian Text Copyright © 2004 by Ozernyuk.
Lev S. Milman, a well known scientist, specialist in
the ﬁeld of developmental biology and biochemistry,
passed away on March 3, 2004. Milman made a signif-
icant contribution to science, above to studies of bio-
chemical problems of ontogenesis. His studies in the
area of nucleic acids and some other areas of biochem-
istry are also well known. He is the author of more than
140 publications, including two monographs published
in our country and abroad.
Lev S. Milman was born in Moscow on November 8,
1926. In 1943 he was called to the ranks of Soviet army
and served at the II Ukrainian front. In 1945–1949, Mil-
man served in the group of Soviet troops in Germany.
The service in Soviet Army and participation in the
Great Patriotic War exerted a great inﬂuence on him
and later he always remembered various episodes of the
military period of his life.
In 1950, Milman entered the Faculty of Biology and
Pedology of the Moscow State University from which
he graduated in 1954 in “plant physiology.” After the
university, he worked at the Central Research Forest-
Technical Institute of the Ministry of Wood Industry
and, from 1957, at the Institute of Animal Morphology
of the USSR Academy of Sciences. The entire subse-
quent scientiﬁc activity of Milman was connected with
this institute (from 1967—Kol’tsov Institute of Devel-
Milman began to work at the Laboratory of Bio-
chemistry of Cell Structures headed by I.B. Zbarsky. At
that time, G.P. Georgiev, O.P. Samarina, V.P. Mant’eva,
L.P. Ermolaeva, K.A. Perevoshchikopva worked in this
laboratory. Here, Milman carried out signiﬁcant studies
on biochemistry of nucleic acids, which constituted the
basis of his candidate (PhD) thesis “A Study of Nucleic
Acids in Cytoplasm of Animal Cells,” which he
defended at the Bakh Institute of Biochemistry, USSR
Academy of Sciences, in 1961.
In 1963, Milman was transferred to the Group of
Space Biology organized and headed by A.I. Zotin and
A.A. Neyfakh, which was reorganized in 1965 into two
groups: Developmental Biophysics (A.I. Zotin) and
Developmental Biochemistry (A.A. Neyfakh). In 1967,
when Institute of Developmental Bioilogy was orga-
nized, the Group of Developmental Biophuysics was
reorganized into the Laboratory of Developmental
Biiophysics, where Milman worked to his last day.
In the Laboratory of Developmental Biiophysics,
Milman worked for many years together with
Yurii G. Yurovitzky and, later, with Lyudmila P. Ermo-
laeva. This was a fruitful long-term cooperation, which
resulted in a new trend in biochemical embryology.
Milman and Yurovitzky carried out fundamental studies
of the regulation of carbohydrate metabolism during
early ontogenesis of ﬁsh. The patterns of carbohydrate
metabolism in early development were ﬁst studied on
the example of ﬁsh embryogenesis. They found that the
ratio of glycolytic and glconeogenetic processes
changes at different stages of development during
oocyte growth, maturation, fertilization and at different
embryonic stages. This conclusion was based on the
bulk of experimental material concerning the estima-
tion of activities and kinetic properties of the enzymes
of glycolysis, glycogenolysis, gluconeogenesis, and
hexose monophosphate bypass, as well of concentra-
tion of the corresponding metabolites during early
development in ﬁsh. These studies became classical
and were widely recognized in this country and abroad.
In 1970, Milman defended his doctoral (D.Sc.) the-
sis “Regulation of Glycolysis and Coupled Processes in
Early Embryogenesis of the Loach.” The results of this
work constituted the basis of two monographs written
Lev S. Milman (1926–2004)