Strahlenther Onkol (2018) 194:196–205 https://doi.org/10.1007/s00066-017-1213-y ORIGINAL ARTICLE Left-sided breast cancer and risks of secondary lung cancer and ischemic heart disease Effects of modern radiotherapy techniques 1 1 1 1 Stefanie Corradini · Hendrik Ballhausen · Helmut Weingandt · Philipp Freislederer · 1 1 2 2 1,3 Stephan Schönecker · Maximilian Niyazi · Cristoforo Simonetto · Markus Eidemüller · Ute Ganswindt · Claus Belka Received: 7 April 2017 / Accepted: 30 August 2017 / Published online: 15 September 2017 © Springer-Verlag GmbH Deutschland 2017, corrected publication October 2017 Abstract Results The DIBH maneuver resulted in a signiﬁcant re- Purpose Modern breast cancer radiotherapy techniques, duction of the ERR and estimated 10-year excess absolute such as respiratory-gated radiotherapy in deep-inspiration risk for major coronary events compared to FB in 3D-CRT breath-hold (DIBH) or volumetric-modulated arc radiother- plans (p = 0.04). In VMAT plans, the mean predicted risk apy (VMAT) have been shown to reduce the high dose ex- reduction through DIBH was less pronounced and not sta- posure of the heart in left-sided breast cancer. The aim of tistically signiﬁcant (p = 0.44). The risk of radiation-in- the present study was to comparatively estimate the excess duced secondary lung cancer was
Strahlentherapie und Onkologie – Springer Journals
Published: Sep 15, 2017
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