Background Endovascular left gastric artery (LGA) embolisation has gained significant attention in the treatment of obesity/ morbid obesity and reduction of ghrelin. The objective of this systematic review is to evaluate the recent literature, strengths, limitations and practical aspects of this new procedure in combination with its physiological and anatomical paradigm. Methods A systematic electronic search of literature from 1966 to June 2017 in Medline, CINHAL, Embase, Scopus and Cochrane library in English language and adult subjects was conducted. This search was conducted in accordance with Preferred Reporting in Systematic Review and Meta-Analysis (PRISMA) guidelines. Quality assessment of the articles was performed, using Oxford critical appraisal skills programme (CASP), and their recommendation for practice was examined through National Institute for health Care Excellence (NICE). Inter-related reliability (Cronbach’s Alpha) was assessed between the two independent reviewers. Results Atotal of n = 62 individuals were subjected to LGA embolisation. At 1–3months,7–11% and, at 12 months, 2% weight reduction was associated with ghrelin concentration reduction of 36% at 6 months. There was Haemoglobin A1c reduction (7.4 to 6.3%) and improved quality of life (SF-36 questionnaire) at 6 months (9.5 points) (range, 3.2–17.2). Despite immediate epigastric pain and mucosal ulceration, no long-term adverse
Obesity Surgery – Springer Journals
Published: Apr 3, 2018
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