Laryngopharyngeal Reflux: Current Concepts on Etiology and Pathophysiology and Its Role in Dysphagia

Laryngopharyngeal Reflux: Current Concepts on Etiology and Pathophysiology and Its Role in Dysphagia Purpose of Review Laryngopharyngeal reflux (LPR) is one of the most commonly encountered chronic inflammatory conditions of the larynx. The lack of a unifying consensus regarding diagnosis and management makes it difficult to relate laryngeal disorders and dysphagia to this disease entity, particularly for an otolaryngologist. This article reviews diagnosis and management of LPR from an otolaryngological and gastroenterological perspective by reconciling current trends in the literature. Recent Findings More sophisticated testing via multichannel pH probes as well as the implementation of pepsin assays has potential in diagnosing LPR. This will hopefully more clearly delineate this disease entity, in the setting of dysphagia. Summary Dysphagia and LPR both have significant overlap with numerous disease entities. Though there is little literature to address outcomes in treatment and management of dysphagia in the setting of LPR, few studies show that managing LPR-related dysphagia may improve with surgical intervention if there is no improvement with conservative management. . . . . . . Keywords Laryngopharyngeal reflux (LPR) reflux Laryngoscopy pH probe Empiric treatment Proton pump inhibitor . . . . . Pepsin Gastroesophageal reflux Reflux laryngitis Heartburn Dysphagia Swallowing Introduction at one end of the spectrum and others present with “atypical symptoms.” http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Otorhinolaryngology Reports Springer Journals

Laryngopharyngeal Reflux: Current Concepts on Etiology and Pathophysiology and Its Role in Dysphagia

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Publisher
Springer US
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Otorhinolaryngology
eISSN
2167-583X
D.O.I.
10.1007/s40136-018-0192-6
Publisher site
See Article on Publisher Site

Abstract

Purpose of Review Laryngopharyngeal reflux (LPR) is one of the most commonly encountered chronic inflammatory conditions of the larynx. The lack of a unifying consensus regarding diagnosis and management makes it difficult to relate laryngeal disorders and dysphagia to this disease entity, particularly for an otolaryngologist. This article reviews diagnosis and management of LPR from an otolaryngological and gastroenterological perspective by reconciling current trends in the literature. Recent Findings More sophisticated testing via multichannel pH probes as well as the implementation of pepsin assays has potential in diagnosing LPR. This will hopefully more clearly delineate this disease entity, in the setting of dysphagia. Summary Dysphagia and LPR both have significant overlap with numerous disease entities. Though there is little literature to address outcomes in treatment and management of dysphagia in the setting of LPR, few studies show that managing LPR-related dysphagia may improve with surgical intervention if there is no improvement with conservative management. . . . . . . Keywords Laryngopharyngeal reflux (LPR) reflux Laryngoscopy pH probe Empiric treatment Proton pump inhibitor . . . . . Pepsin Gastroesophageal reflux Reflux laryngitis Heartburn Dysphagia Swallowing Introduction at one end of the spectrum and others present with “atypical symptoms.”

Journal

Current Otorhinolaryngology ReportsSpringer Journals

Published: May 1, 2018

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