Large Deformation Properties of Red Blood Cell Membrane Based on a Higher Order Gradient Quasi-continuum Model

Large Deformation Properties of Red Blood Cell Membrane Based on a Higher Order Gradient... Based on the proposed higher order gradient quasi-continuum model, the numerical investigations of the basic mechanical properties and deformation behaviors of human red blood cell (RBC) membrane under large deformation at room temperature (i.e., 300 K) are carried out in the present paper. The results show that RBC membrane is a nonlinear hyperelastic material. The mechanical properties of RBC membrane is dominated by isotropic nature at the stage of initial deformation, however, its anisotropic material properties emerge clearly with the loading increasing. The out-of-plane wrinkling of RBC membrane upon shear loading can be reproduced numerically. With the use of the so-called higher order Cauchy–Born rule as the kinematic description, the bending stiffness of RBC membrane can be considered conveniently. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Membrane Biology Springer Journals

Large Deformation Properties of Red Blood Cell Membrane Based on a Higher Order Gradient Quasi-continuum Model

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Publisher
Springer US
Copyright
Copyright © 2015 by Springer Science+Business Media New York
Subject
Life Sciences; Biochemistry, general; Human Physiology
ISSN
0022-2631
eISSN
1432-1424
D.O.I.
10.1007/s00232-015-9809-6
Publisher site
See Article on Publisher Site

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