Lack of restriction of growth for aquareovirus in mammalian cells

Lack of restriction of growth for aquareovirus in mammalian cells The striped bass (SBR) virus, a member of the recently described aquareoviruses, infected, caused cytopathic effects (CPE), and replicated in mammalian cells. The virus caused CPE in all 7 of the mammalian cell lines investigated. SBR virus functioned best at lower temperatures and it is these lower temperatures that appeared to be restricting factors for growth of some mammalian cells. At 22 °C the SBR virus grew to similar titers in both chinook salmon embryo (CHSE) cells and in mammalian cells. Analysis of viral polypeptide and RNA synthesis suggests that the restriction for viral growth at higher temperatures occurs after adsorption but before transcription and translation of viral genes. The fact that SBR virus did not grow at 37 °C implies that aquareo- viruses are unlikely to be human pathogens. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Lack of restriction of growth for aquareovirus in mammalian cells

Loading next page...
 
/lp/springer_journal/lack-of-restriction-of-growth-for-aquareovirus-in-mammalian-cells-OMmLWpTylA
Publisher
Springer Journals
Copyright
Copyright © Wien by 1998 Springer-Verlag/
Subject
Legacy
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s007050050313
Publisher site
See Article on Publisher Site

Abstract

The striped bass (SBR) virus, a member of the recently described aquareoviruses, infected, caused cytopathic effects (CPE), and replicated in mammalian cells. The virus caused CPE in all 7 of the mammalian cell lines investigated. SBR virus functioned best at lower temperatures and it is these lower temperatures that appeared to be restricting factors for growth of some mammalian cells. At 22 °C the SBR virus grew to similar titers in both chinook salmon embryo (CHSE) cells and in mammalian cells. Analysis of viral polypeptide and RNA synthesis suggests that the restriction for viral growth at higher temperatures occurs after adsorption but before transcription and translation of viral genes. The fact that SBR virus did not grow at 37 °C implies that aquareo- viruses are unlikely to be human pathogens.

Journal

Archives of VirologySpringer Journals

Published: Mar 1, 1998

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off