L-lactide ring-opening polymerization on a magnesium catalyst based on acenaphthene-1,2-diimine ligand: Development of biocompatible materials for osteoplasty

L-lactide ring-opening polymerization on a magnesium catalyst based on acenaphthene-1,2-diimine... Isotactic poly-L-lactide was prepared by L-lactide ring-opening polymerization in tetrahydrofuran solution in the presence of a magnesium complex derived from 1,2-bis-[(2,6-diisopropyl)phenylimino]acenaphthene (dpp-bian). Polymer specimens in the form of cylindrical blocks, prepared by hot molding, were tested in experiments with human dermal fibroblast cultures. The polymers prepared exhibit no cytotoxicity, which opens prospects for performing their preclinical animal tests. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Applied Chemistry Springer Journals

L-lactide ring-opening polymerization on a magnesium catalyst based on acenaphthene-1,2-diimine ligand: Development of biocompatible materials for osteoplasty

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Publisher
Pleiades Publishing
Copyright
Copyright © 2017 by Pleiades Publishing, Ltd.
Subject
Chemistry; Chemistry/Food Science, general; Industrial Chemistry/Chemical Engineering
ISSN
1070-4272
eISSN
1608-3296
D.O.I.
10.1134/S1070427216120247
Publisher site
See Article on Publisher Site

Abstract

Isotactic poly-L-lactide was prepared by L-lactide ring-opening polymerization in tetrahydrofuran solution in the presence of a magnesium complex derived from 1,2-bis-[(2,6-diisopropyl)phenylimino]acenaphthene (dpp-bian). Polymer specimens in the form of cylindrical blocks, prepared by hot molding, were tested in experiments with human dermal fibroblast cultures. The polymers prepared exhibit no cytotoxicity, which opens prospects for performing their preclinical animal tests.

Journal

Russian Journal of Applied ChemistrySpringer Journals

Published: Apr 20, 2017

References

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