Access the full text.
Sign up today, get DeepDyve free for 14 days.
C. Remacle, P. Cardol, N. Coosemans, M. Gaisne, N. Bonnefoy (2006)
High-efficiency biolistic transformation of Chlamydomonas mitochondria can be used to insert mutations in complex I genes.Proceedings of the National Academy of Sciences of the United States of America, 103 12
M. Barros, A. Johnson, A. Tzagoloff (2004)
COX23, a Homologue of COX17, Is Required for Cytochrome Oxidase Assembly*Journal of Biological Chemistry, 279
S. Newman, J. Boynton, N. Gillham, Barbara Randolph-Anderson, Anita Johnson, E. Harris (1990)
Transformation of chloroplast ribosomal RNA genes in Chlamydomonas: molecular and genetic characterization of integration events.Genetics, 126 4
P. Cardol, F. Vanrobaeys, B. Devreese, J. Beeumen, R. Matagne, C. Remacle (2004)
Higher plant-like subunit composition of mitochondrial complex I from Chlamydomonas reinhardtii: 31 conserved components among eukaryotes.Biochimica et biophysica acta, 1658 3
P. Cardol, J. Alric, J. Girard‐Bascou, F. Franck, F. Wollman, G. Finazzi (2009)
Impaired respiration discloses the physiological significance of state transitions in ChlamydomonasProceedings of the National Academy of Sciences, 106
C. Remacle, G. Gloire, P. Cardol, R. Matagne (2004)
Impact of a mutation in the mitochondrial LSU rRNA gene from Chlamydomonas reinhardtii on the activity and the assembly of respiratory-chain complexesCurrent Genetics, 45
X Pérez-Martinez, M Vazquez-Acevedo, E Tolkunova, S Funes, MG Claros, E Davidson, MP King, D González-Halphen (2000)
Unusual location of a mitochondrial gene. Subunit III of cytochrome c oxidase is encoded in the nucleus of Chlamydomonad algaeJ Biol Chem, 275
X. Pérez-Martínez, M. Vázquez-Acevedo, E. Tolkunova, S. Funes, M. Claros, E. Davidson, M. King, D. González-Halphen (2000)
Unusual Location of a Mitochondrial GeneThe Journal of Biological Chemistry, 275
M Watanabe, K Henmi, K Ogawa, T Suzuki (2003)
Cadmium-dependent generation of reactive oxygen species and mitochondrial DNA breaks in photosynthetic and non-photosynthetic strains of Euglena gracilisComp Biochem Phys Part C Toxicol Pharmacol, 134
R. Lis, A. Atteia, G. Mendoza-Hernández, D. González-Halphen (2003)
Identification of Novel Mitochondrial Protein Components ofChlamydomonas reinhardtii. A Proteomic Approach1Plant Physiology, 132
P. Cardol, R. Matagne, C. Remacle (2002)
Impact of mutations affecting ND mitochondria-encoded subunits on the activity and assembly of complex I in Chlamydomonas. Implication for the structural organization of the enzyme.Journal of molecular biology, 319 5
E. Harris (2009)
The Chlamydomonas sourcebook
S. Leary, B. Kaufman, G. Pellecchia, Guy-Hellen Guercin, A. Mattman, M. Jaksch, E. Shoubridge (2004)
Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase.Human molecular genetics, 13 17
Sylvie Gillet, P. Decottignies, Solenne Chardonnet, P. Maréchal (2006)
Cadmium response and redoxin targets in Chlamydomonas reinhardtii: a proteomic approachPhotosynthesis Research, 89
M. Schroda (2006)
RNA silencing in Chlamydomonas: mechanisms and toolsCurrent Genetics, 49
W. Pulich, C. Ward (1973)
Physiology and Ultrastructure of an Oxygen-resistant Chlorella Mutant under Heterotrophic Conditions.Plant physiology, 51 2
P. Cardol, D. González-Halphen, A. Reyes-Prieto, D. Baurain, R. Matagne, C. Remacle (2005)
The Mitochondrial Oxidative Phosphorylation Proteome of Chlamydomonas reinhardtii Deduced from the Genome Sequencing Project1Plant Physiology, 137
M. Fuhrmann, Alke Stahlberg, E. Govorunova, Simone Rank, P. Hegemann (2001)
The abundant retinal protein of the Chlamydomonas eye is not the photoreceptor for phototaxis and photophobic responses.Journal of cell science, 114 Pt 21
W. Yanamura, Y. Zhang, S. Takamiya, R. Capaldi (1988)
Tissue-specific differences between heart and liver cytochrome c oxidase.Biochemistry, 27 13
An Jamers, K. Ven, L. Moens, J. Robbens, G. Potters, Y. Guisez, R. Blust, W. Coen (2006)
Effect of copper exposure on gene expression profiles in Chlamydomonas reinhardtii based on microarray analysis.Aquatic toxicology, 80 3
B. Meunier (2001)
Site-directed mutations in the mitochondrially encoded subunits I and III of yeast cytochrome oxidase.The Biochemical journal, 354 Pt 2
Britta Förster, C. Osmond, B. Pogson (2005)
Improved survival of very high light and oxidative stress is conferred by spontaneous gain-of-function mutations in Chlamydomonas.Biochimica et biophysica acta, 1709 1
T. Balandin, C. Castresana (2002)
AtCOX17, an Arabidopsis Homolog of the Yeast Copper Chaperone COX171Plant Physiology, 129
P. Cardol, F. Figueroa, C. Remacle, L. Franzén, D. González-Halphen (2009)
Oxidative Phosphorylation: Building Blocks and Related Components
M. Hanikenne, P. Motte, M. Wu, Tingliang Wang, R. Loppes, R. Matagne (2005)
A mitochondrial half‐size ABC transporter is involved in cadmium tolerance in Chlamydomonas reinhardtiiPlant Cell and Environment, 28
H. Schägger, G. Jagow (1991)
Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form.Analytical biochemistry, 199 2
C. Attallah, E. Welchen, D. Gonzalez (2007)
The promoters of Arabidopsis thaliana genes AtCOX17‐1 and ‐2, encoding a copper chaperone involved in cytochrome c oxidase biogenesis, are preferentially active in roots and anthers and induced by biotic and abiotic stressPhysiologia Plantarum, 129
M. Nóbrega, Simone Bandeira, J. Beers, A. Tzagoloff (2002)
Characterization of COX19, a Widely Distributed Gene Required for Expression of Mitochondrial Cytochrome Oxidase*The Journal of Biological Chemistry, 277
C. Remacle, F. Duby, P. Cardol, R. Matagne (2001)
Mutations inactivating mitochondrial genes in Chlamydomonas reinhardtii.Biochemical Society transactions, 29 Pt 4
Marie Lapaille, Adelma Escobar-Ramírez, H. Degand, D. Baurain, E. Rodríguez-Salinas, N. Coosemans, M. Boutry, D. González-Halphen, C. Remacle, P. Cardol (2010)
Atypical subunit composition of the chlorophycean mitochondrial F1FO-ATP synthase and role of Asa7 protein in stability and oligomycin resistance of the enzyme.Molecular biology and evolution, 27 7
Daniel Daley, Keith Adams, R. Clifton, S. Qualmann, A. Millar, Jeffrey Palmer, E. Pratje, J. Whelan (2002)
Gene transfer from mitochondrion to nucleus: novel mechanisms for gene activation from Cox2.The Plant journal : for cell and molecular biology, 30 1
R. Balaban, S. Nemoto, T. Finkel (2005)
Mitochondria, Oxidants, and AgingCell, 120
F. Duby, R. Matagne (1999)
Alteration of Dark Respiration and Reduction of Phototrophic Growth in a Mitochondrial DNA Deletion Mutant of Chlamydomonas Lacking cob, nd4, and the 3′ End of nd5Plant Cell, 11
S. Merchant, S. Prochnik, O. Vallon, E. Harris, Steven Karpowicz, G. Witman, A. Terry, A. Salamov, Lillian Fritz-Laylin, L. Marechal-Drouard, W. Marshall, L. Qu, D. Nelson, A. Sanderfoot, M. Spalding, V. Kapitonov, Q. Ren, P. Ferris, E. Lindquist, H. Shapiro, S. Lucas, J. Grimwood, J. Schmutz, P. Cardol, H. Cerutti, G. Chanfreau, Chun-long Chen, V. Cognat, M. Croft, Rachel Dent, S. Dutcher, E. Fernández, H. Fukuzawa, David González-Ballester, D. González-Halphen, A. Hallmann, M. Hanikenne, M. Hippler, W. Inwood, K. Jabbari, M. Kalanon, R. Kuras, P. Lefebvre, S. Lemaire, A. Lobanov, M. Lohr, A. Manuell, I. Meier, L. Mets, M. Mittag, T. Mittelmeier, J. Moroney, J. Moseley, C. Napoli, A. Nedelcu, K. Niyogi, S. Novoselov, I. Paulsen, G. Pazour, S. Purton, J. Ral, D. Riaño-Pachón, W. Riekhof, Linda Rymarquis, M. Schroda, D. Stern, J. Umen, R. Willows, N. Wilson, Sara Zimmer, J. Allmer, J. Balk, K. Bišová, Chong Chen, M. Eliáš, K. Gendler, C. Hauser, M. Lamb, H. Ledford, J. Long, J. Minagawa, M. Page, Junmin Pan, W. Pootakham, S. Roje, A. Rose, E. Stahlberg, A. Terauchi, Pinfen Yang, S. Ball, C. Bowler, C. Dieckmann, V. Gladyshev, P. Green, R. Jorgensen, S. Mayfield, B. Mueller‐Roeber, S. Rajamani, R. Sayre, P. Brokstein, I. Dubchak, D. Goodstein, Leila Hornick, Y. Huang, Jinal Jhaveri, Yi Luo, Diego Martínez, W. Ngau, Bobby Otillar, Alexander Poliakov, Aaron Porter, L. Szajkowski, Gregory Werner, Kemin Zhou, I. Grigoriev, D. Rokhsar, A. Grossman (2007)
The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant FunctionsScience, 318
P. Palumaa, L. Kangur, Anastassia Voronova, R. Sillard (2004)
Metal-binding mechanism of Cox17, a copper chaperone for cytochrome c oxidase.The Biochemical journal, 382 Pt 1
Y. Horng, P. Cobine, A. Maxfield, H. Carr, D. Winge (2004)
Specific Copper Transfer from the Cox17 Metallochaperone to Both Sco1 and Cox11 in the Assembly of Yeast Cytochrome c Oxidase*Journal of Biological Chemistry, 279
Masumi Watanabe, K. Henmi, K. Ogawa, Tetsuya Suzuki (2003)
Cadmium-dependent generation of reactive oxygen species and mitochondrial DNA breaks in photosynthetic and non-photosynthetic strains of Euglena gracilis.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 134 2
R. Loppes, M. Radoux (2002)
Two short regions of the promoter are essential for activation and repression of the nitrate reductase gene in Chlamydomonas reinhardtiiMolecular Genetics and Genomics, 268
J. Hosler, S. Ferguson-Miller, D. Mills (2006)
Energy transduction: proton transfer through the respiratory complexes.Annual review of biochemistry, 75
J. Keightley, Kristen Hoffbuhr, Miriam Burton, Virginia Salas, Wendy Johnston, Andrew Penn, Neil Buist, N. Kennaway (1996)
A microdeletion in cytochrome c oxidase (COX) subunit III associated with COX deficiency and recurrent myoglobinuriaNature Genetics, 12
Holger Eubel, L. Jänsch, H. Braun (2003)
New Insights into the Respiratory Chain of Plant Mitochondria. Supercomplexes and a Unique Composition of Complex II
Jeanette Quinn, Paola Barraco, M. Eriksson, S. Merchant (2000)
Coordinate Copper- and Oxygen-responsive Cyc6 andCpx1 Expression in Chlamydomonas Is Mediated by the Same Element*The Journal of Biological Chemistry, 275
P. Cardol, Marie Lapaille, Pierre Minet, F. Franck, R. Matagne, C. Remacle (2006)
ND3 and ND4L Subunits of Mitochondrial Complex I, Both Nucleus Encoded in Chlamydomonas reinhardtii, Are Required for Activity and Assembly of the EnzymeEukaryotic Cell, 5
G. Michaelis, C. Vahrenholz, E. Pratje (1990)
Mitochondrial DNA of Chlamydomonas reinhardtii: The gene for apocytochrome b and the complete functional map of the 15.8 kb DNAMolecular and General Genetics MGG, 223
Jeanette Quinn, H. Li, J. Singer, B. Morimoto, Laurens Mets, K. Kindle, S. Merchant (1993)
The plastocyanin-deficient phenotype of Chlamydomonas reinhardtii Ac-208 results from a frame-shift mutation in the nuclear gene encoding preapoplastocyanin.The Journal of biological chemistry, 268 11
Jinshui Fan, Robert Lee (2002)
Mitochondrial genome of the colorless green alga Polytomella parva: two linear DNA molecules with homologous inverted repeat Termini.Molecular biology and evolution, 19 7
C. Remacle, D. Baurain, P. Cardol, R. Matagne (2001)
Mutants of Chlamydomonas reinhardtii deficient in mitochondrial complex I: characterization of two mutations affecting the nd1 coding sequence.Genetics, 158 3
K. Wilson, L. Prochaska (1990)
Phospholipid vesicles containing bovine heart mitochondrial cytochrome c oxidase and subunit III-deficient enzyme: analysis of respiratory control and proton translocating activities.Archives of biochemistry and biophysics, 282 2
C. Oswald, U. Krause-Buchholz, G. Rödel (2009)
Knockdown of human COX17 affects assembly and supramolecular organization of cytochrome c oxidase.Journal of molecular biology, 389 3
J. Hosler (2004)
The influence of subunit III of cytochrome c oxidase on the D pathway, the proton exit pathway and mechanism-based inactivation in subunit I.Biochimica et biophysica acta, 1655 1-3
Kristen Hoffbuhr, E. Davidson, Beth Filiano, M. Davidson, N. Kennaway, M. King (2000)
A Pathogenic 15-Base Pair Deletion in Mitochondrial DNA-encoded Cytochrome c Oxidase Subunit III Results in the Absence of Functional Cytochrome c Oxidase*The Journal of Biological Chemistry, 275
M. Bradford (1976)
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.Analytical biochemistry, 72
Glerum Dm, A. Shtanko, A. Tzagoloff (1996)
Characterization of COX17, a Yeast Gene Involved in Copper Metabolism and Assembly of Cytochrome Oxidase*The Journal of Biological Chemistry, 271
X. Pérez-Martínez, A. Antaramián, M. Vázquez-Acevedo, S. Funes, E. Tolkunova, J. d'Alayer, M. Claros, E. Davidson, M. King, D. González-Halphen (2001)
Subunit II of Cytochrome c Oxidase in Chlamydomonad Algae Is a Heterodimer Encoded by Two Independent Nuclear Genes*The Journal of Biological Chemistry, 276
W. Mages, O. Heinrich, Gerda Treuner, D. Vlček, Ivana Daubnerová, M. Slaninová (2007)
Complementation of the Chlamydomonas reinhardtii arg7-8 (arg2) point mutation by recombination with a truncated nonfunctional ARG7 gene.Protist, 158 4
K. Kindle (1990)
High-frequency nuclear transformation of Chlamydomonas reinhardtii.Proceedings of the National Academy of Sciences of the United States of America, 87
J Quinn, HH Li, J Singer, B Morimoto, L Mets, K Kindle, S Merchant (1993)
The plastocyanin-deficient phenotype of Chlamydomonas reinhardtii Ac-208 results from a frame-shift mutation in the nuclear gene encoding preapoplastocyaninJ Biol Chem, 268
J. Taanman, R. Capaldi (1992)
Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme.The Journal of biological chemistry, 267 31
The COX3 gene encodes a core subunit of mitochondrial cytochrome c oxidase (complex IV) whereas the COX17 gene encodes a chaperone delivering copper to the enzyme. Mutants of these two genes were isolated by RNA interference in the microalga Chlamydomonas. The COX3 mRNA was completely lacking in the cox3-RNAi mutant and no activity and assembly of complex IV were detected. The cox17-RNAi mutant presented a reduced level of COX17 mRNA, a reduced activity of the cytochrome c oxidase but no modification of its amount. The cox3-RNAi mutant had only 40% of the wild-type rate of dark respiration which was cyanide-insensitive. The mutant presented a 60% decrease of H2O2 production in the dark compared to wild type, which probably accounts for a reduced electron leakage by respiratory complexes III and IV. In contrast, the cox17-RNAi mutant showed no modification of respiration and of H2O2 production in the dark but a two to threefold increase of H2O2 in the light compared to wild type and the cox3-RNAi mutant. The cox17-RNAi mutant was more sensitive to cadmium than the wild-type and cox3-RNAi strains. This suggested that besides its role in complex IV assembly, Cox17 could have additional functions in the cell such as metal detoxification or Reactive Oxygen Species protection or signaling. Concerning Cox3, its role in Chlamydomonas complex IV is similar to that of other eukaryotes although this subunit is encoded in the nuclear genome in the alga contrary to the situation found in all other organisms.
Plant Molecular Biology – Springer Journals
Published: Aug 11, 2010
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.