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Graefes Arch Clin Exp Ophthalmol (2017) 255:1843–1850 DOI 10.1007/s00417-017-3703-0 ONCOLOGY Juxtapapillary and circumpapillary choroidal melanoma: globe-sparing treatment outcomes with iodine-125 notched plaque brachytherapy 1 2 2 1 John V. Hegde & Tara A. McCannel & Colin A. McCannel & James Lamb & 1 1 2 1 Pin-Chieh Wang & Darlene Veruttipong & Robert Almanzor & D. Jeffrey Demanes & Mitchell Kamrava Received: 6 December 2016 /Revised: 24 April 2017 /Accepted: 30 May 2017 /Published online: 9 June 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract Median circumferential optic disc involvement was 50% Purpose Managing juxtapapillary and circumpapillary choroi- (range 10%–100%). Eye retention was achieved in 94.1%. dal melanoma with brachytherapy is challenging because of Actuarial 2- and 4-year rates of local recurrence were 3.1% technical complications with accurate plaque placement and and 7.6%, DMFS were 97.0% and 88.5%, CSS were 97.0% high radiation toxicity given tumor proximity to the optic nerve. and 92.8%, and OS were 97.0% and 88.9%, respectively. In We evaluated our center’s experience using ultrasound-guided, addition, 23.5% had visual acuity ≥20/200 at last follow-up. Iodine (I)-125 notched plaque brachytherapy for treating cho- Conclusions I-125 notched plaque brachytherapy provides roidal melanoma contiguous with (juxtapapillary) and at least high eye
Graefe's Archive for Clinical and Experimental Ophthalmology – Springer Journals
Published: Jun 9, 2017
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