Graefes Arch Clin Exp Ophthalmol (2017) 255:1843–1850 DOI 10.1007/s00417-017-3703-0 ONCOLOGY Juxtapapillary and circumpapillary choroidal melanoma: globe-sparing treatment outcomes with iodine-125 notched plaque brachytherapy 1 2 2 1 John V. Hegde & Tara A. McCannel & Colin A. McCannel & James Lamb & 1 1 2 1 Pin-Chieh Wang & Darlene Veruttipong & Robert Almanzor & D. Jeffrey Demanes & Mitchell Kamrava Received: 6 December 2016 /Revised: 24 April 2017 /Accepted: 30 May 2017 /Published online: 9 June 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract Median circumferential optic disc involvement was 50% Purpose Managing juxtapapillary and circumpapillary choroi- (range 10%–100%). Eye retention was achieved in 94.1%. dal melanoma with brachytherapy is challenging because of Actuarial 2- and 4-year rates of local recurrence were 3.1% technical complications with accurate plaque placement and and 7.6%, DMFS were 97.0% and 88.5%, CSS were 97.0% high radiation toxicity given tumor proximity to the optic nerve. and 92.8%, and OS were 97.0% and 88.9%, respectively. In We evaluated our center’s experience using ultrasound-guided, addition, 23.5% had visual acuity ≥20/200 at last follow-up. Iodine (I)-125 notched plaque brachytherapy for treating cho- Conclusions I-125 notched plaque brachytherapy provides roidal melanoma contiguous with (juxtapapillary) and at least high eye
Graefe's Archive for Clinical and Experimental Ophthalmology – Springer Journals
Published: Jun 9, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera