J Membrane Biol (2016) 249:9 DOI 10.1007/s00232-016-9901-6 Amitabha Chattopadhyay Published online: 18 April 2016 Springer Science+Business Media New York 2016 Biological membranes act as a unique interface between above-mentioned overlapping features of biological mem- cells and provide individual identity to them. They are branes with disease progression. The Journal of Membrane complex, dynamic, anisotropic ﬂuids with interesting Biology (JMBI), in its new avatar, will focus on this con- physicochemical aspects. The relationship between mem- nection between membranes and disease. Of course, there branes and diseases has its genesis in a number of inter- is nothing in membrane research that is not interdisci- esting factors related to membranes. A remarkable aspect plinary, and membrane literature with implications in dis- of membrane proteins is their ability to act as drug targets. eases will clearly have its biophysical, biochemical, and It is estimated that *50 % of currently prescribed drugs in cell biological components. At the end of the day, judicious all clinical areas target membrane proteins. In addition, the and intelligent use of these techniques will provide novel quasi-two-dimensional nature of membranes allows an insights into biological membrane research related to dis- increase in the local concentration of pathogenic proteins, eases. This should lead to an overall improvement in the such as amyloidogenic peptides, giving rise to diseases of quality of human life across the globe, a goal shared by all misfolding induced by crowding. Another corner stone in practitioners of modern biology. the membrane-disease paradigm is the fact that any intra- I look forward to submissions from you to JMBI in the cellular pathogen has to cross the plasma membrane of the new section, Membranes in Disease, in the broadest con- host cell to establish an infection, thereby allowing a text. I hope the JMBI community will identify this section handle on the entry of pathogens by manipulating host and establish a vibrant, interactive group in this area. membrane composition. In the post-genomic era of modern biology, research on biological membranes assumes greater relevance due to the & Amitabha Chattopadhyay firstname.lastname@example.org Center of Cellular and Molecular Biology, Uppal Road, Hyderabad, India
The Journal of Membrane Biology – Springer Journals
Published: Apr 18, 2016
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