Isoperistaltic versus antiperistaltic side-to-side anastomosis after right laparoscopic hemicolectomy for cancer (ISOVANTI) trial: study protocol for a randomised clinical trial

Isoperistaltic versus antiperistaltic side-to-side anastomosis after right laparoscopic... Background It is believed that loosing ileocecal valve is well as antiperistaltic anastomosis can be considered has short- or tolerated in patients who do not have short bowel syndrome or long-term consequences in gastrointestinal habit. Considering Crohn disease. From the hypothesis of colonic peristalsis and the impact that ileocolic anastomosis configuration could have transit is regulated by that ileocecal valvular mechanism, we on the restitution of bowel transit after right hemicolectomy, try to find out if the creation of a new pseudo-valvular mech- we think it is indicated and necessary a randomized trial com- anism as antiperistaltic anastomosis could be considered after paring iso- and antiperistaltic modalities. right hemicolectomy can cause any short- or long-term chang- Trial registration NCT02309931 es in gastrointestinal habits. . . Purpose The purpose of the study at primary endpoint is to Keywords Isoperistaltic Antiperistaltic Ileocaecal compare early (occurring within 30 days of surgery) and late anastomosis Right hemicolectomy (occurring during the follow-up) postoperative complications between both groups The purpose of the study at secondary endpoint is to com- Background pare intraoperative and postoperative events between experi- mental and control groups in terms of operating time, first oral Rationale tolerance day, first flatus and faeces, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Colorectal Disease Springer Journals

Isoperistaltic versus antiperistaltic side-to-side anastomosis after right laparoscopic hemicolectomy for cancer (ISOVANTI) trial: study protocol for a randomised clinical trial

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; Surgery; Internal Medicine; Gastroenterology; Hepatology; Proctology
ISSN
0179-1958
eISSN
1432-1262
D.O.I.
10.1007/s00384-017-2840-6
Publisher site
See Article on Publisher Site

Abstract

Background It is believed that loosing ileocecal valve is well as antiperistaltic anastomosis can be considered has short- or tolerated in patients who do not have short bowel syndrome or long-term consequences in gastrointestinal habit. Considering Crohn disease. From the hypothesis of colonic peristalsis and the impact that ileocolic anastomosis configuration could have transit is regulated by that ileocecal valvular mechanism, we on the restitution of bowel transit after right hemicolectomy, try to find out if the creation of a new pseudo-valvular mech- we think it is indicated and necessary a randomized trial com- anism as antiperistaltic anastomosis could be considered after paring iso- and antiperistaltic modalities. right hemicolectomy can cause any short- or long-term chang- Trial registration NCT02309931 es in gastrointestinal habits. . . Purpose The purpose of the study at primary endpoint is to Keywords Isoperistaltic Antiperistaltic Ileocaecal compare early (occurring within 30 days of surgery) and late anastomosis Right hemicolectomy (occurring during the follow-up) postoperative complications between both groups The purpose of the study at secondary endpoint is to com- Background pare intraoperative and postoperative events between experi- mental and control groups in terms of operating time, first oral Rationale tolerance day, first flatus and faeces,

Journal

International Journal of Colorectal DiseaseSpringer Journals

Published: Jun 21, 2017

References

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