Isolation and localization of the skeletal myosin heavy chain 2X gene on pig chromosome 12q1.4-q1.5

Isolation and localization of the skeletal myosin heavy chain 2X gene on pig chromosome 12q1.4-q1.5 Mammalian Genome 9, Brief Data Reports Elba some segregation. Intracellular distribution of CAPTS protein Chromosomes were identified in accordance with the recommen- dations by the Committee for the Standardized Karyotype of the mimicks that of tubulin, that is, CAPTS appears to be associated Domestic Pig [4]. with, but not to be an integral part of, microtubules [6]. The fact that CSE1 and CAPTS are highly conserved in eukaryotes, to- Previously identified homologs: The skeletal myosin heavy chain gether with the observation that CSE1 is essential in yeast, indi- (MYH) genes have been mapped to human Chr 17p13.1 [5,6]. This cluster contains the 2X isoform and at least five other MYH genes cates that it might play important roles in cell division and prob- ably also in cell cycle regulation. [5]. In the mouse, these genes are clustered on Chr 11 (Myhsf1) [7]. Acknowledgment: This work was supported in part by the National Cancer Results and Discussion: Myosin is the major component of Institute, Department of Health and Human Services, under contract with muscle sarcomeres and is composed of two heavy chains (MYHs) ABL. and four light chains. Skeletal muscle MYHs occur in a number of isoforms, encoded by genes Mammalian Genome Springer Journals

Isolation and localization of the skeletal myosin heavy chain 2X gene on pig chromosome 12q1.4-q1.5

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Copyright © 1998 by Springer-Verlag
Life Sciences; Cell Biology; Anatomy; Zoology
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