Is it possible to detect PEth 16:0/18:1 and PEth 18:1/18:1 in red blood cells after 20years of storage in liquid nitrogen?

Is it possible to detect PEth 16:0/18:1 and PEth 18:1/18:1 in red blood cells after 20years of... Int J Legal Med (2017) 131:1291–1297 DOI 10.1007/s00414-017-1626-2 SHORT COMMUNICATION Is it possible to detect PEth 16:0/18:1 and PEth 18:1/18:1 in red blood cells after 20 years of storage in liquid nitrogen? 1 2 2 2 1 Robert Boll & Theron Johnson & Rudolf Kaaks & Tilman Kühn & Gisela Skopp Received: 20 February 2017 /Accepted: 12 June 2017 /Published online: 24 June 2017 Springer-Verlag GmbH Germany 2017 Abstract 1 month of storage at −80 °C. Our data suggest that PEth is Introduction Phosphatidylethanol (PEth), as measured in generally also detectable in samples after 20 years of storage at freshly drawn blood samples, could be a promising new bio- −196 °C. Further studies are needed to assess the still un- marker for habitual alcohol consumption, but it is still un- known impact of storage duration and temperature on differ- known whether PEth can also be determined from blood sam- ent PEth specimen concentrations. ples having been stored frozen for a longer period. Materials and methods PEth 16:0/18:1 and PEth 18:1/18:1 . Keywords Phosphatidylethanol (PEth) Habitual alcohol . . were determined by LC-MS/MS from red blood cells (RBC) consumption EPIC-Heidelberg study Long-term storage derived from blood samples of (I) 20 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Legal Medicine Springer Journals

Is it possible to detect PEth 16:0/18:1 and PEth 18:1/18:1 in red blood cells after 20years of storage in liquid nitrogen?

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; Forensic Medicine; Medical Law; Medicine/Public Health, general
ISSN
0937-9827
eISSN
1437-1596
D.O.I.
10.1007/s00414-017-1626-2
Publisher site
See Article on Publisher Site

Abstract

Int J Legal Med (2017) 131:1291–1297 DOI 10.1007/s00414-017-1626-2 SHORT COMMUNICATION Is it possible to detect PEth 16:0/18:1 and PEth 18:1/18:1 in red blood cells after 20 years of storage in liquid nitrogen? 1 2 2 2 1 Robert Boll & Theron Johnson & Rudolf Kaaks & Tilman Kühn & Gisela Skopp Received: 20 February 2017 /Accepted: 12 June 2017 /Published online: 24 June 2017 Springer-Verlag GmbH Germany 2017 Abstract 1 month of storage at −80 °C. Our data suggest that PEth is Introduction Phosphatidylethanol (PEth), as measured in generally also detectable in samples after 20 years of storage at freshly drawn blood samples, could be a promising new bio- −196 °C. Further studies are needed to assess the still un- marker for habitual alcohol consumption, but it is still un- known impact of storage duration and temperature on differ- known whether PEth can also be determined from blood sam- ent PEth specimen concentrations. ples having been stored frozen for a longer period. Materials and methods PEth 16:0/18:1 and PEth 18:1/18:1 . Keywords Phosphatidylethanol (PEth) Habitual alcohol . . were determined by LC-MS/MS from red blood cells (RBC) consumption EPIC-Heidelberg study Long-term storage derived from blood samples of (I) 20

Journal

International Journal of Legal MedicineSpringer Journals

Published: Jun 24, 2017

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