Int J Legal Med (2017) 131:1291–1297 DOI 10.1007/s00414-017-1626-2 SHORT COMMUNICATION Is it possible to detect PEth 16:0/18:1 and PEth 18:1/18:1 in red blood cells after 20 years of storage in liquid nitrogen? 1 2 2 2 1 Robert Boll & Theron Johnson & Rudolf Kaaks & Tilman Kühn & Gisela Skopp Received: 20 February 2017 /Accepted: 12 June 2017 /Published online: 24 June 2017 Springer-Verlag GmbH Germany 2017 Abstract 1 month of storage at −80 °C. Our data suggest that PEth is Introduction Phosphatidylethanol (PEth), as measured in generally also detectable in samples after 20 years of storage at freshly drawn blood samples, could be a promising new bio- −196 °C. Further studies are needed to assess the still un- marker for habitual alcohol consumption, but it is still un- known impact of storage duration and temperature on differ- known whether PEth can also be determined from blood sam- ent PEth specimen concentrations. ples having been stored frozen for a longer period. Materials and methods PEth 16:0/18:1 and PEth 18:1/18:1 . Keywords Phosphatidylethanol (PEth) Habitual alcohol . . were determined by LC-MS/MS from red blood cells (RBC) consumption EPIC-Heidelberg study Long-term storage derived from blood samples of (I) 20
International Journal of Legal Medicine – Springer Journals
Published: Jun 24, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera