Introduction to mammalian genome special issue: genetics of behavior

Introduction to mammalian genome special issue: genetics of behavior Mamm Genome (2014) 25:1–2 DOI 10.1007/s00335-013-9496-5 Introduction to mammalian genome special issue: genetics of behavior Lisa M. Tarantino Leonard C. Schalkwyk Published online: 25 January 2014 Springer Science+Business Media New York 2014 The Brain Initiative, a multi-year project in the US aimed associated with behavioral phenotypes. These early studies, at mapping brain activity, will begin in 2014. A similar while useful, were limited by low power due to the sample initiative in the European Union, The Human Brain Pro- size limitations of existing experimental populations. Lar- ject, has recently started, and 2014 has been designated as ger studies of intercross or backcross populations between ‘‘The Year of the Brain’’ by the European Brain Council. It two inbred mouse strains increased power, but reduced is obvious that worldwide, a renewed emphasis has been resolution to detect manageable QTL regions in which to placed on understanding the specifics of how the brain effectively identify candidate genes. As a result, hundreds works to produce ‘‘normal’’ behaviors and, by extension, of QTL for behavior have been reported to date, but only a how these processes can go wrong and result in psychiatric handful of genes have been identified using these and neurodevelopmental disease. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Introduction to mammalian genome special issue: genetics of behavior

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Publisher
Springer US
Copyright
Copyright © 2014 by Springer Science+Business Media New York
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s00335-013-9496-5
Publisher site
See Article on Publisher Site

Abstract

Mamm Genome (2014) 25:1–2 DOI 10.1007/s00335-013-9496-5 Introduction to mammalian genome special issue: genetics of behavior Lisa M. Tarantino Leonard C. Schalkwyk Published online: 25 January 2014 Springer Science+Business Media New York 2014 The Brain Initiative, a multi-year project in the US aimed associated with behavioral phenotypes. These early studies, at mapping brain activity, will begin in 2014. A similar while useful, were limited by low power due to the sample initiative in the European Union, The Human Brain Pro- size limitations of existing experimental populations. Lar- ject, has recently started, and 2014 has been designated as ger studies of intercross or backcross populations between ‘‘The Year of the Brain’’ by the European Brain Council. It two inbred mouse strains increased power, but reduced is obvious that worldwide, a renewed emphasis has been resolution to detect manageable QTL regions in which to placed on understanding the specifics of how the brain effectively identify candidate genes. As a result, hundreds works to produce ‘‘normal’’ behaviors and, by extension, of QTL for behavior have been reported to date, but only a how these processes can go wrong and result in psychiatric handful of genes have been identified using these and neurodevelopmental disease.

Journal

Mammalian GenomeSpringer Journals

Published: Jan 25, 2014

References

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