Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2582-z) contains supplementary material, which is available to authorized users. & Malek Taher Maghsoodlou email@example.com Department of Chemistry, University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran 123 8110 F. O. Chahkamali et al. Keywords Multi-component reaction Substituted piperidines SbI3 Simple procedure Introduction The synthesis and chemistry of heterocyclic compounds are appealing areas of research in organic chemistry, in particular because a signiﬁcant number of natural compounds contain a heterocyclic portion. The application of heterocycles in biology, pharmacology, material sciences, and medicine, as well as agriculture is very well-known . Additionally, the majority of antibiotics and vitamins include heterocyclic rings in their structure . In recent years multi-component reactions (MCRs), deﬁned as reactions in which more than two reactants are combined to give a product that comprises a majority of the involved atoms, have played an outstanding role in synthetic organic chemistry. These reactions are powerful tools for the construction of novel and complex molecular structures with a minimum number of synthetic steps. Distinguishing features of MCRs include high efﬁciency, simplicity, time-saving processes, and atom economy [3–6]. Piperidines and their analogues are an essential building
Research on Chemical Intermediates – Springer Journals
Published: Jun 6, 2016
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