Introduction ISSN 1022-7954, Russian Journal of Genetics, 2006, Vol. 42, No. 9, p. 957. © Pleiades Publishing, Inc., 2006. Original Russian Text © I.F. Zhimulev, L.I. Korochkin, 2006, published in Genetika, 2006, Vol. 42, No. 9, p. 1155. DOI: 10.1134/S1022795406090018 This issue of the journal is devoted to a special A.I. Shevchenko et al. consider current evidence on theme, epigenetics, which is among the most intensely epigenetic inactivation of total chromosomes or their developing branches of genetics. The term epigenetic parts. V.N. Stegniy discusses evolutionary processes of very often refers to completely different events and chromosome architectonics as a possible form of epige- mechanisms, but in general this field studies interaction netic control of eukaryotic ontogeny and phylogeny; of genes and environment that provide the development E.S. Platonov and D.A. Isaev discuss genomic imprint- of the normal phenotype. In this process, hereditary ing in epigenetics. changes of the genomic functions occur without any V.A. Sokolov presented a review on imprinting in change in the DNA sequences. plants; B.F. Chadov, on large modifications in Droso- Epigenetics covers the issues of how the gene phila; R.N. Tchuraev, on gene and epigene networks in expression patterns in one cell are transmitted to its ontogeny and phylogeny. progeny without changes. This, in its turn, is connected A number of articles on epigenetics were published in to DNA packaging in actively functioning cells and to other issues of the journal: in the paper by T.D. Kolesni- the organization of the chromatin structure. kova et al. (Russian Journal of Genetics, 2006, no. 8), In the world literature, the issues of epigenetics receive the evidence on the properties of protein SUUR, spe- particular attention. Recently, an Internet site has been cific for epigenetic silencing regions, are overviewed; opened ( the paper by O.G. Maksimenko et al. (Russian Journal netics.php), presenting information on problems of epi- of Genetics, 2006, no. 8) reviews the data on gene genetics, experimental protocols, and lectures of enhancers; A.P. Dyban and P.A. Dyban consider theo- renowned authors in this filed. In addition, this site pro- retical and applied aspects of epigenetics (published in vides information on booking tests of 21 lectures on Russian Journal of Genetics, 2006, no. 12). Finally, different problems of epigenetics, prepared by promi- S.V. Razin presented a review on the spatial eukaryotic nent world scientists. genome organization as an epigenetic factor (Russian This issue of the Russian Journal of Genetics pre- Journal of Genetics, 2006, no. 12). sents articles by modern Russian authors. Definition of the term epigenetics and methodology of epigenetic The problems considered in this issue of the journal are very diverse both with regard to methods and scien- processes are considered by L.I. Korochkin; the morpho- mechanical aspects of epigenesis, by L.V. Belousov. tific problems of epigenetics. The Editorial Board D.E. Koryakov discusses molecular aspects of the hopes that these papers will prove useful and interest- chromatin organization, while B.F. Vanyushin, the dis- ing to a broad range of researchers. coverer of DNA methylation, reviews the history of the concept of DNA modification upon inactivation of genes. The papers by A.V. Vershinin and I.F. Zhimulev, L.I. Korochkin Russian Journal of Genetics Springer Journals
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Biomedicine; Human Genetics; Microbial Genetics and Genomics; Animal Genetics and Genomics
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