Intravenous immunoglobulins for treatment of connective tissue diseases in dermatology

Intravenous immunoglobulins for treatment of connective tissue diseases in dermatology review Wien Med Wochenschr (2018) 168:213–217 https://doi.org/10.1007/s10354-017-0595-x Intravenous immunoglobulins for treatment of connective tissue diseases in dermatology Lyubomir A. Dourmishev · Dimitrina V. Guleva · Ljubka G. Miteva Received: 19 June 2017 / Accepted: 4 August 2017 / Published online: 1 September 2017 © Springer-Verlag GmbH Austria 2017 Summary Keywords Connective tissue diseases · Intravenous Background Connective tissue diseases are a het- immunoglobulins · Therapeutic regiments · Adverse erogeneous group of autoimmune disorders affecting effects · Cost effectiveness not only skin, but also various organs and systems. First-line treatment of connective tissue diseases is systemic steroids as monotherapy or combined with Connective tissue diseases are a heterogeneous group immunosuppressive drugs. Since intravenous im- of autoimmune disorders affecting the skin as well as munoglobulins (IVIGs) have been found to be ef- various organs and systems. Their pathogenesis in- fective for various autoimmune dermatoses, their cludes contributions of genetic and environment fac- indications have expanded tremendously. tors that trigger apoptosis, leading to initiation of cel- Objective The aim this review article is to highlight lular cytotoxicity with autoantibody formation. the indications, effectiveness, and side effects of high Intravenous immunoglobulins (IVIGs) were initially dosesimmunoglobulinsfor treatmentofpatientswith used by Bruton in 1952 [1] as http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Wiener Medizinische Wochenschrift Springer Journals

Intravenous immunoglobulins for treatment of connective tissue diseases in dermatology

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Publisher
Springer Vienna
Copyright
Copyright © 2017 by Springer-Verlag GmbH Austria
Subject
Medicine & Public Health; Medicine/Public Health, general; Pharmacology/Toxicology; General Practice / Family Medicine; Geriatrics/Gerontology; Internal Medicine; Infectious Diseases
ISSN
0043-5341
eISSN
1563-258X
D.O.I.
10.1007/s10354-017-0595-x
Publisher site
See Article on Publisher Site

Abstract

review Wien Med Wochenschr (2018) 168:213–217 https://doi.org/10.1007/s10354-017-0595-x Intravenous immunoglobulins for treatment of connective tissue diseases in dermatology Lyubomir A. Dourmishev · Dimitrina V. Guleva · Ljubka G. Miteva Received: 19 June 2017 / Accepted: 4 August 2017 / Published online: 1 September 2017 © Springer-Verlag GmbH Austria 2017 Summary Keywords Connective tissue diseases · Intravenous Background Connective tissue diseases are a het- immunoglobulins · Therapeutic regiments · Adverse erogeneous group of autoimmune disorders affecting effects · Cost effectiveness not only skin, but also various organs and systems. First-line treatment of connective tissue diseases is systemic steroids as monotherapy or combined with Connective tissue diseases are a heterogeneous group immunosuppressive drugs. Since intravenous im- of autoimmune disorders affecting the skin as well as munoglobulins (IVIGs) have been found to be ef- various organs and systems. Their pathogenesis in- fective for various autoimmune dermatoses, their cludes contributions of genetic and environment fac- indications have expanded tremendously. tors that trigger apoptosis, leading to initiation of cel- Objective The aim this review article is to highlight lular cytotoxicity with autoantibody formation. the indications, effectiveness, and side effects of high Intravenous immunoglobulins (IVIGs) were initially dosesimmunoglobulinsfor treatmentofpatientswith used by Bruton in 1952 [1] as

Journal

Wiener Medizinische WochenschriftSpringer Journals

Published: Sep 1, 2017

References

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