review Wien Med Wochenschr (2018) 168:213–217 https://doi.org/10.1007/s10354-017-0595-x Intravenous immunoglobulins for treatment of connective tissue diseases in dermatology Lyubomir A. Dourmishev · Dimitrina V. Guleva · Ljubka G. Miteva Received: 19 June 2017 / Accepted: 4 August 2017 / Published online: 1 September 2017 © Springer-Verlag GmbH Austria 2017 Summary Keywords Connective tissue diseases · Intravenous Background Connective tissue diseases are a het- immunoglobulins · Therapeutic regiments · Adverse erogeneous group of autoimmune disorders affecting effects · Cost effectiveness not only skin, but also various organs and systems. First-line treatment of connective tissue diseases is systemic steroids as monotherapy or combined with Connective tissue diseases are a heterogeneous group immunosuppressive drugs. Since intravenous im- of autoimmune disorders affecting the skin as well as munoglobulins (IVIGs) have been found to be ef- various organs and systems. Their pathogenesis in- fective for various autoimmune dermatoses, their cludes contributions of genetic and environment fac- indications have expanded tremendously. tors that trigger apoptosis, leading to initiation of cel- Objective The aim this review article is to highlight lular cytotoxicity with autoantibody formation. the indications, effectiveness, and side effects of high Intravenous immunoglobulins (IVIGs) were initially dosesimmunoglobulinsfor treatmentofpatientswith used by Bruton in 1952  as
Wiener Medizinische Wochenschrift – Springer Journals
Published: Sep 1, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera