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T. Day, J. Bennett, R. Pax (1992)
Schistosoma mansoni: patch-clamp study of a nonselective cation channel in the outer tegumental membrane of females.Experimental parasitology, 74 3
(1993)
Temporal correlations in Ca
A. Kilejian, L. Schinazi, C. Schwabe (1961)
Host-parasite relationships in echinococcosis. V. Histochemical observations on Echinococcus granulosus.The Journal of parasitology, 47
C. Mitchell, T. Jacob (1996)
A Nonselective High Conductance Channel in Bovine Pigmented Ciliary Epithelial CellsThe Journal of Membrane Biology, 150
Claudio Grosman, I. Reisin (1995)
Echinococcus granulosus: partial characterization of the conductive properties of two cation channels from protoscoleces of the ovine strain, reconstituted on planar lipid bilayers.Experimental parasitology, 81 4
L. Chappell (1980)
The biology of the external surfaces of helminth parasitesProceedings of The Royal Society B: Biological Sciences, 79
(1994)
Physiological and pharmacological properties of muscle cells isolated from the flatworm
A. Siddiqui, R. Podesta (1985)
Subcellular fractionation of Hymenolepis diminuta with special reference to the localization of marker enzymes.The Journal of parasitology, 71 4
K. Blair, P. Anderson (1993)
PROPERTIES OF 185TAGE-ACTIVATED IONIC CURRENTS IN CELLS FROM THE BRAINS OF THE TRICLAD FLATWORM BDELLOURA CANDIDAThe Journal of Experimental Biology, 185
(1981)
3 HOHOsmotic water fluxes and ultrastructure of an epithelial synctium
D. McManus, N. Barrett (1985)
Isolation, fractionation and partial characterization of the tegumental surface from protoscoleces of the hydatid organism, Echinococcus granulosusParasitology, 90
A. Ferreira, T. Trecu, I. Reisin (1992)
Echinococcus granulosus: study of the in vitro complement activation by protoscoleces by measuring the electric potential difference across the tegumental membrane.Experimental parasitology, 75 3
A. Zahradníková, I. Zahradník (1995)
Description of modal gating of the cardiac calcium release channel in planar lipid membranes.Biophysical journal, 69 5
J. Patlak, K. Gration, Peter Usherwood (1979)
Single glutamate-activated channels in locust muscleNature, 278
T. Day, N. Orr, J. Bennett, R. Pax (1993)
Voltage-gated currents in muscle cells of Schistosoma mansoniParasitology, 106
D. Colquhoun, F. Sigworth (1983)
Fitting and Statistical Analysis of Single-Channel Records
C. Ibarra, I. Reisin (1994)
Echinococcus granulosus: characterization of the electrical potential of the syncytial tegument of protoscoleces incubated in vitro--effect of inhibitors.Experimental parasitology, 78 4
P. Hess, J. Lansman, R. Tsien (1984)
Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonistsNature, 311
A. Blatz, K. Magleby (1986)
Quantitative description of three modes of activity of fast chloride channels from rat skeletal muscle.The Journal of Physiology, 378
K. Blair, T. Day, M. Lewis, J. Bennett, R. Pax (1991)
Studies on muscle cells isolated from Schistosoma mansoni: a Ca2+-dependent K+ channelParasitology, 102
F. Cohen, W. Niles (1993)
Reconstituting channels into planar membranes: a conceptual framework and methods for fusing vesicles to planar bilayer phospholipid membranes.Methods in enzymology, 220
O. Alvarez, D. Benos, R. Latorre (1985)
The study of ion channels in planar lipid bilayer membranes, 12
H. Matsunaga, B. Stanton, F. Gesek, P. Friedman (1994)
Epithelial Ca2+ channels sensitive to dihydropyridines and activated by hyperpolarizing voltages.The American journal of physiology, 267 1 Pt 1
S. Silberberg, A. Lagrutta, J. Adelman, K. Magleby (1996)
Wanderlust kinetics and variable Ca(2+)-sensitivity of Drosophila, a large conductance Ca(2+)-activated K+ channel, expressed in oocytes.Biophysical journal, 70 6
E. Moczydlowski, R. Latorre (1983)
Gating kinetics of Ca2+-activated K+ channels from rat muscle incorporated into planar lipid bilayers. Evidence for two voltage- dependent Ca2+ binding reactionsThe Journal of General Physiology, 82
E. Moczydlowski, R. Latorre
Gating Kinetics of Ca "-activated K + Channels from Rat Muscle Incorporated into Planar Lipid Bilayers Evidence for Two Voltage-dependent Ca 2 ' Binding Reactions
O. McManus, K. Magleby (1988)
Kinetic states and modes of single large‐conductance calcium‐activated potassium channels in cultured rat skeletal muscle.The Journal of Physiology, 402
D. Morseth (1967)
Fine structure of the hydatid cyst and protoscolex of Echinococcus granulosus.The Journal of parasitology, 53 2
A 107-pS (symmetrical 150 mm KCl), nonselective cation channel was reconstituted from a microsomal membrane fraction of the larval stage of the tapeworm Echinococcus granulosus. Most of the time, it displayed a high open probability (>0.95) irrespective of either the applied voltage, Ca2+, Ba2+, or tetraethylammonium concentration. Nevertheless, in contrast with this ``leaklike'' behavior, less frequently this ``all-the-time-open'' channel reversibly entered two different kinetic modes. One of them was characterized by lower P o values and some voltage sensitivity (V ½≅ 129 mV, and an equilibrium constant for channel closing changing e-fold per 63-mV change) the kinetic analysis revealing that it resulted from the appearance of voltage-sensitivity in the mean closed times and a sixfold increase in the equilibrium constant for channel closing at 0 mV. The other mode was characterized by a very fast open-close activity leading to poorly resolved current levels and a P o around 0.6–0.7 which, occasionally and in a voltage-sensitive manner, entered a long-lived nonconducting state. However, the rare nature of these mode-shifting transitions precluded a more detailed analysis of their kinetics. The conductive properties of the channel were not affected by these switches. Model gating alone does not seem to ensure any physiological role of this channel and, instead, some other channel changes must occur if this phenomenon were to be of regulatory importance in vivo. Thus, mode-shifting might constitute an alternative target for channel activity modulation also in tapeworms.
The Journal of Membrane Biology – Springer Journals
Published: Jul 1, 1997
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