Breast Cancer Res Treat (2017) 165:421–431 DOI 10.1007/s10549-017-4341-2 EPIDEMIOLOGY Interaction of mammographic breast density with menopausal status and postmenopausal hormone use in relation to the risk of aggressive breast cancer subtypes 1 2,3 4 • • • Lusine Yaghjyan Rulla M. Tamimi Kimberly A. Bertrand 5 5 5 • • • Christopher G. Scott Matthew R. Jensen V. Shane Pankratz 6 7 8 8,9 • • • • Kathy Brandt Daniel Visscher Aaron Norman Fergus Couch 10 11 11 12 13 • • • • • John Shepherd Bo Fan Yunn-Yi Chen Lin Ma Andrew H. Beck 14 15,16 8 • • Steven R. Cummings Karla Kerlikowske Celine M. Vachon Received: 9 January 2017 / Accepted: 13 June 2017 / Published online: 17 June 2017 Springer Science+Business Media, LLC 2017 Abstract Study, Nurses’ Health Study II, and San Francisco Mam- Purpose We examined the associations of mammographic mography Registry. Percent breast density (PD), absolute breast density with breast cancer risk by tumor aggres- dense (DA), and non-dense areas (NDA) were assessed siveness and by menopausal status and current post- from digitized ﬁlm-screen mammograms using a com- menopausal hormone therapy. puter-assisted threshold technique and standardized across Methods This study included
Breast Cancer Research and Treatment – Springer Journals
Published: Jun 17, 2017
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