Innovative technique using heterogenous collagen and intermingled autologous split-thickness skin graft for coverage of raw areas in deep burns with paucity of donor site as a life-saving measure

Innovative technique using heterogenous collagen and intermingled autologous split-thickness skin... Burns injuries are extremely complex and elicit physiological and metabolic interactions involving all major organ systems. These pathological changes occur in a time dependent manner. In the last decades, burn care has improved, so the trend in the current treatment extends beyond the preservation of life. Thus, ultimate goal is complete rehabilitation of the burn victims. To investigate the effectiveness of the use of heterogenous collagen and intermingled autologous split-thickness skin for early coverage of raw areas in deep burns with paucity of donorsite as a life saving measure. A total of 10 subjects between the age group of 5 to 30 years (mean age 22 years) who sustained deep burns with total burn area from 60% to 80% (mean 72 %) and full thickness burn from 40% to 50% (mean 44 %) were treated with collagen and autologous split thickness graft sheets. Complete wound epithelialization took between 30 to 50 days.Rejection of collagen within 5 days was observed in only 1 out of 10 subjects and 2 subjects demonstrated incomplete epithelialization. A total of 9 out of 10 patients survived and 1 patient expereienced death due to an acute rejection reaction. The combination of collagen andsplit thickness skin grafting is an effective method to cover the wounds and achieved satisfactory healing pattern, a minimal rejection phenomenon and good survival rates. Moreover, it can be efficient as a life saving measure in deep burns with few donor areas available for grafting specially for developing and third world nations where expensive facilities like CEA are not feasible. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

Innovative technique using heterogenous collagen and intermingled autologous split-thickness skin graft for coverage of raw areas in deep burns with paucity of donor site as a life-saving measure

Loading next page...
 
/lp/springer_journal/innovative-technique-using-heterogenous-collagen-and-intermingled-WR7xh80C0S
Publisher
Springer-Verlag
Copyright
Copyright © 2011 by Springer-Verlag
Subject
Medicine & Public Health; Plastic Surgery
ISSN
0930-343X
eISSN
1435-0130
D.O.I.
10.1007/s00238-010-0475-8
Publisher site
See Article on Publisher Site

Abstract

Burns injuries are extremely complex and elicit physiological and metabolic interactions involving all major organ systems. These pathological changes occur in a time dependent manner. In the last decades, burn care has improved, so the trend in the current treatment extends beyond the preservation of life. Thus, ultimate goal is complete rehabilitation of the burn victims. To investigate the effectiveness of the use of heterogenous collagen and intermingled autologous split-thickness skin for early coverage of raw areas in deep burns with paucity of donorsite as a life saving measure. A total of 10 subjects between the age group of 5 to 30 years (mean age 22 years) who sustained deep burns with total burn area from 60% to 80% (mean 72 %) and full thickness burn from 40% to 50% (mean 44 %) were treated with collagen and autologous split thickness graft sheets. Complete wound epithelialization took between 30 to 50 days.Rejection of collagen within 5 days was observed in only 1 out of 10 subjects and 2 subjects demonstrated incomplete epithelialization. A total of 9 out of 10 patients survived and 1 patient expereienced death due to an acute rejection reaction. The combination of collagen andsplit thickness skin grafting is an effective method to cover the wounds and achieved satisfactory healing pattern, a minimal rejection phenomenon and good survival rates. Moreover, it can be efficient as a life saving measure in deep burns with few donor areas available for grafting specially for developing and third world nations where expensive facilities like CEA are not feasible.

Journal

European Journal of Plastic SurgerySpringer Journals

Published: Apr 1, 2011

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off