Informatics resources for the Collaborative Cross and related mouse populations

Informatics resources for the Collaborative Cross and related mouse populations Mamm Genome (2015) 26:521–539 DOI 10.1007/s00335-015-9581-z Informatics resources for the Collaborative Cross and related mouse populations 1 2 Andrew P. Morgan Catherine E. Welsh Received: 16 March 2015 / Accepted: 23 June 2015 / Published online: 2 July 2015 Springer Science+Business Media New York 2015 Introduction remains mostly unexplored—has limited the number of extant lines to *150 at time of writing. Nonetheless, the CC The Collaborative Cross (CC) and the complementary has begun to fulfill its promise as a source of extreme Diversity Outbred (DO) population were conceived as a phenotypic variability and associated candidate loci (Iraqi platform for the next generation of studies of the genetic et al. 2014). Within just the past year, CC lines have been basis for complex traits in mouse (Churchill et al. 2004). shown to be highly variable for traits related to both normal The CC promised to combine the strengths of existing physiology and disease, including gene expression in panels of recombinant inbred (RI) lines [e.g., BXD (Taylor healthy liver (Aylor et al. 2011; Weiser et al. 2014), allergic et al. 1973), LXS (Williams et al. 2004)] and inbred strains airway inflammation (Kelada et al. 2014), lymphocyte (Ghazalpour et al. 2012)—phenotypic variation, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Informatics resources for the Collaborative Cross and related mouse populations

Loading next page...
 
/lp/springer_journal/informatics-resources-for-the-collaborative-cross-and-related-mouse-BV00lr5Bob
Publisher
Springer US
Copyright
Copyright © 2015 by Springer Science+Business Media New York
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s00335-015-9581-z
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial