Influence of principal component analysis acceleration factor on velocity measurement in 2D and 4D PC-MRI

Influence of principal component analysis acceleration factor on velocity measurement in 2D and... Objective The objective of the study was to determine how to optimize 2D and 4D phase-contrast magnetic resonance imag- ing (PC-MRI) acquisitions to acquire flow velocities in millimetric vessels. In particular, we search for the best compromise between acquisition time and accuracy and assess the influence of the principal component analysis (PCA). Materials and methods 2D and 4D PC-MRI measurements are conducted within two in vitro vessel phantoms: a Y-bifur- cation phantom, the branches of which range from 2 to 5 mm in diameter, and a physiological subject-specific phantom of the carotid bifurcation. The same sequences are applied in vivo in carotid vasculature. Results For a vessel oriented in the axial direction, both 2D and axial 4D PC-MRI provided accuracy measurements regard- less of the k-t PCA factor, while the acquisition time is reduced by a factor 6 for k-t PCA maximum value. The in vivo measurements show that the proposed sequences are adequate to acquire 2D and 4D velocity fields in millimetric vessels and with clinically realistic time durations. Conclusion The study shows the feasibility of conducting fast, high-resolution PC-MRI flow measurements in millimetric vessels and that it is worth maximizing the k-t PCA factor to reduce the acquisition time in the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Magnetic Resonance Materials in Physics, Biology and Medicine Springer Journals

Influence of principal component analysis acceleration factor on velocity measurement in 2D and 4D PC-MRI

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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by ESMRMB
Subject
Medicine & Public Health; Imaging / Radiology; Computer Appl. in Life Sciences; Solid State Physics; Biomedical Engineering; Health Informatics
ISSN
0968-5243
eISSN
1352-8661
D.O.I.
10.1007/s10334-018-0673-0
Publisher site
See Article on Publisher Site

Abstract

Objective The objective of the study was to determine how to optimize 2D and 4D phase-contrast magnetic resonance imag- ing (PC-MRI) acquisitions to acquire flow velocities in millimetric vessels. In particular, we search for the best compromise between acquisition time and accuracy and assess the influence of the principal component analysis (PCA). Materials and methods 2D and 4D PC-MRI measurements are conducted within two in vitro vessel phantoms: a Y-bifur- cation phantom, the branches of which range from 2 to 5 mm in diameter, and a physiological subject-specific phantom of the carotid bifurcation. The same sequences are applied in vivo in carotid vasculature. Results For a vessel oriented in the axial direction, both 2D and axial 4D PC-MRI provided accuracy measurements regard- less of the k-t PCA factor, while the acquisition time is reduced by a factor 6 for k-t PCA maximum value. The in vivo measurements show that the proposed sequences are adequate to acquire 2D and 4D velocity fields in millimetric vessels and with clinically realistic time durations. Conclusion The study shows the feasibility of conducting fast, high-resolution PC-MRI flow measurements in millimetric vessels and that it is worth maximizing the k-t PCA factor to reduce the acquisition time in the

Journal

Magnetic Resonance Materials in Physics, Biology and MedicineSpringer Journals

Published: Jan 22, 2018

References

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