Clin Res Cardiol (2018) 107:222–232 DOI 10.1007/s00392-017-1174-2 ORIGINAL PAPER Influence of hydrostatic pressure on intracoronary indices of stenosis severity in vivo 1 1 1 1 Tobias Härle · Mareike Luz · Sven Meyer · Felix Vahldiek · 2,3 2,3 2,3 4 Pim van der Harst · Randy van Dijk · Daan Ties · Javier Escaned · 5 1 Justin Davies · Albrecht Elsässer Received: 29 August 2017 / Accepted: 26 October 2017 / Published online: 2 November 2017 © Springer-Verlag GmbH Germany 2017 Abstract CI 0.029–0.057, p < 0.0001), and of resting Pd/Pa 0.037 Background An influence of hydrostatic pressure on intra- (SD 0.034, 95% CI 0.025–0.049, p < 0.0001). Addition of coronary indices of stenosis severity in vitro was recently the physically expectable hydrostatic pressure to the dis- reported. We sought to analyze the influence of hydrostatic tal coronary pressures of the control group abolished the pressure, caused by the height difference between the distal differences: corrected ∆FFR − 0.006 (SD 0.027, 95% CI and proximal pressure sensor after guidewire positioning in − 0.015 to 0.004, p = 0.26), corrected ∆Pd/Pa − 0.008 (SD the interrogated vessel, on intracoronary pressure measure- 0.03, 95% CI − 0.019 to 0.003, p = 0.18). Adjustment for ments in vivo. hydrostatic pressure of FFR values in a standard supine posi-
Zeitschrift für Kardiologie – Springer Journals
Published: Nov 2, 2017
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