Influence of Gd-EOB-DTPA on T1 dependence of the proton density fat fraction using magnetic resonance spectroscopy

Influence of Gd-EOB-DTPA on T1 dependence of the proton density fat fraction using magnetic... This phantom study assessed the effect of Gd-EOB-DTPA on T 1 bias (difference in T 1 between water and fat) of the proton density fat fraction when using magnetic resonance spectroscopy. Phantoms containing varying fat percentages, without and with Gd-EOB-DTPA (precontrast and postcontrast, respectively), were scanned with repetition times ranging from 1000 to 5000 ms. The relationship between the proton density fat fraction at a reference repetition time of 5000 ms and that using different repetition times, was evaluated in the precontrast and postcontrast phantoms using linear regression and Bland–Altman analyses. In the precontrast phantom, as the repetition time increased, the slope tended to approach one. In the postcontrast phantom, the slope and intercept were near one and zero, respectively. The mean difference was smaller in the postcontrast phantom (range − 0.24 to − 0.01%) than in the precontrast phantom (range 0.12 to 3.52%). We conclude that I1 bias is minimized by Gd-EOB-DTPA. Keywords Fat · Gd-EOB-DTPA · Liver · Magnetic resonance spectroscopy · Phantom · Quantification 1 Introduction shift-encoded MR imaging (CSE-MRI) method or an MR spectroscopy (MRS) method [6]. The fat volume calculated Liver biopsy remains the gold standard for quantification using MR methods is known as the proton density fat frac- of fat http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Radiological Physics and Technology Springer Journals

Influence of Gd-EOB-DTPA on T1 dependence of the proton density fat fraction using magnetic resonance spectroscopy

Loading next page...
 
/lp/springer_journal/influence-of-gd-eob-dtpa-on-t1-dependence-of-the-proton-density-fat-ltpPsPwSce
Publisher
Springer Singapore
Copyright
Copyright © 2018 by Japanese Society of Radiological Technology and Japan Society of Medical Physics
Subject
Medicine & Public Health; Imaging / Radiology; Nuclear Medicine; Radiotherapy; Medical and Radiation Physics
ISSN
1865-0333
eISSN
1865-0341
D.O.I.
10.1007/s12194-018-0466-1
Publisher site
See Article on Publisher Site

Abstract

This phantom study assessed the effect of Gd-EOB-DTPA on T 1 bias (difference in T 1 between water and fat) of the proton density fat fraction when using magnetic resonance spectroscopy. Phantoms containing varying fat percentages, without and with Gd-EOB-DTPA (precontrast and postcontrast, respectively), were scanned with repetition times ranging from 1000 to 5000 ms. The relationship between the proton density fat fraction at a reference repetition time of 5000 ms and that using different repetition times, was evaluated in the precontrast and postcontrast phantoms using linear regression and Bland–Altman analyses. In the precontrast phantom, as the repetition time increased, the slope tended to approach one. In the postcontrast phantom, the slope and intercept were near one and zero, respectively. The mean difference was smaller in the postcontrast phantom (range − 0.24 to − 0.01%) than in the precontrast phantom (range 0.12 to 3.52%). We conclude that I1 bias is minimized by Gd-EOB-DTPA. Keywords Fat · Gd-EOB-DTPA · Liver · Magnetic resonance spectroscopy · Phantom · Quantification 1 Introduction shift-encoded MR imaging (CSE-MRI) method or an MR spectroscopy (MRS) method [6]. The fat volume calculated Liver biopsy remains the gold standard for quantification using MR methods is known as the proton density fat frac- of fat

Journal

Radiological Physics and TechnologySpringer Journals

Published: Jun 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off