Clin Transl Oncol (2017) 19:1125–1132 DOI 10.1007/s12094-017-1649-7 RESEARCH AR TIC L E Inﬂammation-based indexes and clinicopathologic features are strong predictive values of preoperative circulating tumor cell detection in gastric cancer patients 1 1 1 1 1 1 • • • • • L. Zheng K. Zou C. Yang F. Chen T. Guo B. Xiong Received: 12 December 2016 / Accepted: 13 March 2017 / Published online: 17 March 2017 Federacio ´ n de Sociedades Espan ˜ olas de Oncologı ´a (FESEO) 2017 Abstract analysis showed that SII (p\ 0.001), NLR (p\ 0.001), Purpose Circulating tumor cell (CTC) count and the host PLR (p\ 0.001), and PNI (p \ 0.001) were signiﬁcantly inﬂammatory response are two independent predictors for associated with positive CTC count and CTC detection patients with various malignant disease. Several inﬂam- rate. mation-based indicators have been demonstrated to have Conclusions This study provides evidence that preopera- prognostic value in many malignant solid tumors, including tive indicators consisting of SII, NLR, PLR, and PNI are systemic immune-inﬂammation index (SII), neutrophil robust predictors for CTC detection in gastric cancer lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), patients undergoing tumor resection. and prognostic nutrition index (PNI). The aim of this
Clinical and Translational Oncology – Springer Journals
Published: Mar 17, 2017
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