Eur J Plast Surg (2006) 29: 38–40
N. Tan Baser
U. Balci Akbuga
Infantile digital fibromatosis: late results of two different
Received: 6 January 2005 / Accepted: 2 November 2005 / Published online: 16 March 2006
# Springer-Verlag 2006
Abstract Infantile digital fibromatosis is a rare childhood
benign tumor that mainly affects digits of hands and feet.
Spontaneous regression has been reported, leaving the
treatment options of observation or surgery a controversial
topic. In this article, two cases of infantile digital fibroma-
tosis treated with different approaches are presented.
Observation alone was utilized in the first case. No
spontaneous regression was observed after 2 years of
follow up. In the second case, extended tumor excision and
grafting was the chosen treatment. Recurrence was not
observed at the 24th month postsurgery.
We believe that to prevent recurrence, the tumor must be
Keywords Infantile digital fibromatosis
Infantile digital fibromatosis (IDF) is a benign, asymptom-
atic, nodular, fibrous tissue proliferation, which is gen-
erally localized on the lateral or dorsal surfaces of the digits
of hands and feet .
It is a rare fibrous tumor that affects infants and young
children. Although one third of cases are observed at birth,
most appear during the first 2 years of life. The two sexes
are affected equally. IDF frequently appears as single or
multiple hard, pink, and flat masses on the dorsal or lateral
surfaces of the feet and hands, but it does not occur on the
thumbs or the great toes . Some atypical locations such
as the tongue, breast, nose, arm, and oral cavity have also
been reported . Recurrent IDF was first recognized by
Reye  in 1965. However, similar lesions were reported
previously by Sakurane in 1924 and Stout in 1954 .
The histopathologic and electron microscopic features of
IDF are unique and easily recognized. Pathognomonic
histopathologic characteristics include interlacing fascicles
of spindle-shaped cells and collagen bundles. These bun-
dles form a dermal nodule that may extend into the
subcutaneous tissue. These features are not found in other
fibromatoses. Eosinophilic inclusion bodies are commonly
observed within the cytoplasm of the fibroblasts . These
have been previously regarded as viral-based. However,
later studies did not support a viral etiology . Immu-
nohistochemical and ultrastructural analyses have shown
these inclusions to be composed of aggregations of dense
actin microfilaments .
There are approximately 104 reported cases of IDF in the
available literature . Despite this, there is still no
common approach for treatment. In this article, two cases
of IDF treated with two different approaches are presented
and compared with the current literature.
A 7-month-old baby was admitted to our outpatient clinic
with a history of swelling on the left third toe since birth.
Examination revealed a solitary, erythematous, firm nodule
1.5×1.0 cm on the dorsal aspect of the distal phalanx
(Fig. 1). The mass did not cause functional impairment or
N. Tan Baser (*)
U. Balci Akbuga
Ankara Training and Research Hospital,
Department of Plastic and Reconstructive Surgery,
Cebeci, Ankara, Turkey
N. Tan Baser
499 Sokak Arý Sitesi, No: 46 Çayyolu,