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Induced Production of Furan Derivatives in a Fungal Endophyte Ceriporia lacerate HS-ZJUT-C13A by the Osmac Method

Induced Production of Furan Derivatives in a Fungal Endophyte Ceriporia lacerate HS-ZJUT-C13A by... The One Strain Many Compounds (OSMAC) method was employed to explore the chemical diversities of secondary metabolites produced by Ceriporia lacerate HS-ZJUT-C13A, a fungal endophyte of Huperzia serrata. Four new furan derivatives 1–4, together with a known compound, were obtained from the rice culture of the fungus. The structures of the new compounds were established by detailed analysis of the spectroscopic data, especially 1D and 2D NMR, and HR-ESI-MS. All compounds were evaluated for their acetylcholinesterase inhibitory activity and antiproliferative activities against HeLa, HepG2, and SGC7901 cell lines. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chemistry of Natural Compounds Springer Journals

Induced Production of Furan Derivatives in a Fungal Endophyte Ceriporia lacerate HS-ZJUT-C13A by the Osmac Method

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Pharmacy; Pharmacy; Organic Chemistry; Plant Sciences
ISSN
0009-3130
eISSN
1573-8388
DOI
10.1007/s10600-018-2377-0
Publisher site
See Article on Publisher Site

Abstract

The One Strain Many Compounds (OSMAC) method was employed to explore the chemical diversities of secondary metabolites produced by Ceriporia lacerate HS-ZJUT-C13A, a fungal endophyte of Huperzia serrata. Four new furan derivatives 1–4, together with a known compound, were obtained from the rice culture of the fungus. The structures of the new compounds were established by detailed analysis of the spectroscopic data, especially 1D and 2D NMR, and HR-ESI-MS. All compounds were evaluated for their acetylcholinesterase inhibitory activity and antiproliferative activities against HeLa, HepG2, and SGC7901 cell lines.

Journal

Chemistry of Natural Compounds – Springer Journals

Published: Jun 7, 2018

References