Eur J Appl Physiol (2017) 117:1817–1831 DOI 10.1007/s00421-017-3674-1 ORIGINAL ARTICLE Indexes of cerebral autoregulation do not reflect impairment in syncope: insights from head‑up tilt test of vasovagal and autonomic failure subjects 1 2 1 3 1 Pedro Castro · João Freitas · Rosa Santos · Ronney Panerai · Elsa Azevedo Received: 27 March 2017 / Accepted: 26 June 2017 / Published online: 5 July 2017 © Springer-Verlag GmbH Germany 2017 Abstract We calculated cerebrovascular resistance index (CVRi), Purpose The study of dynamic cerebral autoregulation critical closing pressure (CrCP) and resistance area product (CA), which adapts cerebral blood flow to arterial blood (RAP), and derived CA continuously from autoregulation pressure (ABP) fluctuations, has been limited in ortho - index [ARI(t)]. static intolerance syndromes, mainly due to its stationary Results With HUTT, AF subjects showed a pronounced prerequisites hardly to meet during maneuvers to provoke decrease in CBFV (−36 ± 17 versus −7 ± 6%, p < 0.0001), syncope itself. New techniques of continuous estimates ABP (−29 ± 27 versus 7 ± 12%, p < 0.0001) and RAP of CA could overcome this pitfall. We aimed to evaluate (−17 ± 23 versus 3 ± 18%, p < 0.0001) but not CVRi CA during head-up tilt test in common conditions causing (p = 0.110). VVS subjects showed progressive cerebral
European Journal of Applied Physiology – Springer Journals
Published: Jul 5, 2017
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