Increased detection of influenza A H16 in the United States

Increased detection of influenza A H16 in the United States As a result of an US interagency avian influenza surveillance effort in wild birds, four isolates of influenza A viruses were initially identified as H7 by hemagglutination inhibition (HI) but subsequently identified as H16 through genetic sequence analysis. We report the development of internal primers for amplification and cycle-sequencing of the full-length H16 gene, increased detection of H16 within the US, and possible steric inhibition or cross-reaction between H7 and H16 antigens during the conventional HI assay. The latter could have critical implications for poultry operations if H16 viruses are detected and mistakenly reported as H7 viruses. Archives of Virology Springer Journals

Increased detection of influenza A H16 in the United States

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Springer Vienna
Copyright © 2008 by Springer-Verlag
Biomedicine; Infectious Diseases; Medical Microbiology ; Virology
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