In vivo evaluation of the bone integration of coated poly(vinyl-alcohol) hydrogel fiber implants

In vivo evaluation of the bone integration of coated poly(vinyl-alcohol) hydrogel fiber implants J Mater Sci: Mater Med (2017) 28:114 DOI 10.1007/s10856-017-5923-6 CLINICAL APPLICATIONS OF BIOMATERIALS Original Research In vivo evaluation of the bone integration of coated poly (vinyl-alcohol) hydrogel fiber implants 1,2 1,3 3 1 ● ● ● ● David Moreau Arthur Villain Manon Bachy Henry Proudhon 4 3 3 1,2 ● ● ● David N. Ku Didier Hannouche Hervé Petite Laurent Corté Received: 18 November 2016 / Accepted: 7 June 2017 © Springer Science+Business Media, LLC 2017 Abstract Recently, it has been shown that constructs of method is proposed to quantify the thickness of this fibrous poly(vinyl alcohol) (PVA) hydrogel fibers reproduce clo- capsule. Implants coated with HA were not significantly sely the tensile behavior of ligaments. However, the bio- osteoconductive, which can be attributed to the slow dis- logical response to these systems has not been explored yet. solution of the selected hydroxyapatite. Overall, these Here, we report the first in vivo evaluation of these implants results confirm the relevance of PVA hydrogel fibers for and focus on the integration in bone, using a rabbit model of ligament reconstruction and adjustments are proposed to bone tunnel healing. Implants consisted in bundles of PVA enhance its osseointegration. hydrogel fibers embedded Journal of Materials Science: Materials in Medicine Springer Journals

In vivo evaluation of the bone integration of coated poly(vinyl-alcohol) hydrogel fiber implants

Loading next page...
Springer US
Copyright © 2017 by Springer Science+Business Media, LLC
Materials Science; Biomaterials; Biomedical Engineering; Regenerative Medicine/Tissue Engineering; Polymer Sciences; Ceramics, Glass, Composites, Natural Materials; Surfaces and Interfaces, Thin Films
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial