In vivo evaluation of the bone integration of coated poly(vinyl-alcohol) hydrogel fiber implants

In vivo evaluation of the bone integration of coated poly(vinyl-alcohol) hydrogel fiber implants J Mater Sci: Mater Med (2017) 28:114 DOI 10.1007/s10856-017-5923-6 CLINICAL APPLICATIONS OF BIOMATERIALS Original Research In vivo evaluation of the bone integration of coated poly (vinyl-alcohol) hydrogel fiber implants 1,2 1,3 3 1 ● ● ● ● David Moreau Arthur Villain Manon Bachy Henry Proudhon 4 3 3 1,2 ● ● ● David N. Ku Didier Hannouche Hervé Petite Laurent Corté Received: 18 November 2016 / Accepted: 7 June 2017 © Springer Science+Business Media, LLC 2017 Abstract Recently, it has been shown that constructs of method is proposed to quantify the thickness of this fibrous poly(vinyl alcohol) (PVA) hydrogel fibers reproduce clo- capsule. Implants coated with HA were not significantly sely the tensile behavior of ligaments. However, the bio- osteoconductive, which can be attributed to the slow dis- logical response to these systems has not been explored yet. solution of the selected hydroxyapatite. Overall, these Here, we report the first in vivo evaluation of these implants results confirm the relevance of PVA hydrogel fibers for and focus on the integration in bone, using a rabbit model of ligament reconstruction and adjustments are proposed to bone tunnel healing. Implants consisted in bundles of PVA enhance its osseointegration. hydrogel fibers embedded http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Materials Science: Materials in Medicine Springer Journals

In vivo evaluation of the bone integration of coated poly(vinyl-alcohol) hydrogel fiber implants

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Materials Science; Biomaterials; Biomedical Engineering; Regenerative Medicine/Tissue Engineering; Polymer Sciences; Ceramics, Glass, Composites, Natural Materials; Surfaces and Interfaces, Thin Films
ISSN
0957-4530
eISSN
1573-4838
D.O.I.
10.1007/s10856-017-5923-6
Publisher site
See Article on Publisher Site

Abstract

J Mater Sci: Mater Med (2017) 28:114 DOI 10.1007/s10856-017-5923-6 CLINICAL APPLICATIONS OF BIOMATERIALS Original Research In vivo evaluation of the bone integration of coated poly (vinyl-alcohol) hydrogel fiber implants 1,2 1,3 3 1 ● ● ● ● David Moreau Arthur Villain Manon Bachy Henry Proudhon 4 3 3 1,2 ● ● ● David N. Ku Didier Hannouche Hervé Petite Laurent Corté Received: 18 November 2016 / Accepted: 7 June 2017 © Springer Science+Business Media, LLC 2017 Abstract Recently, it has been shown that constructs of method is proposed to quantify the thickness of this fibrous poly(vinyl alcohol) (PVA) hydrogel fibers reproduce clo- capsule. Implants coated with HA were not significantly sely the tensile behavior of ligaments. However, the bio- osteoconductive, which can be attributed to the slow dis- logical response to these systems has not been explored yet. solution of the selected hydroxyapatite. Overall, these Here, we report the first in vivo evaluation of these implants results confirm the relevance of PVA hydrogel fibers for and focus on the integration in bone, using a rabbit model of ligament reconstruction and adjustments are proposed to bone tunnel healing. Implants consisted in bundles of PVA enhance its osseointegration. hydrogel fibers embedded

Journal

Journal of Materials Science: Materials in MedicineSpringer Journals

Published: Jun 19, 2017

References

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