Immune globulin

Immune globulin Reactions 1680, p169 - 2 Dec 2017 Supraventricular tachycardia: 2 case reports A neonate girl and a neonate boy [ages at the time of reactions onsets not stated] were described, who developed supraventricular tachycardia (SVT) following administration of immune globulin [dosages not stated]. Case 1: A baby girl was born at 36 weeks of gestation by spontaneous vaginal delivery to a 30-year-old woman. At the th 6 postnatal hour, the baby girl’s bilirubin level was 2.8 mg/dL corresponding to a pathologic rate of increase. She was known to develop an immune haemolysis due to ABO incompatibility and was administered IV infusion of immune globulin to be given over 4 hours. After 75 mins of the immune globulin administration, her HR suddenly increased to 260 beats/min. The electrocardiography revealed narrow QRS SVT. She was treated with adenosine and her HR returned to normal (144/min). Case 2: A baby boy was born at 38 weeks of gestation to a 29-year-old healthy woman. After birth, his umbilical cord bilirubin level increased, corresponding to a pathologic rate of increase. Subsequently, he started receiving IV infusion of immune globulin to be given over 4 hours. Two hours later, his HR suddenly increased to 230 beats/min. The ECG revealed narrow QRS SVT. He was treated with adenosine and his HR returned to normal. However, the SVT episodes recurrent on th th the 5 and 8 days of life, which responded to adenosine th treatment. On the 9 day of his life, the SVT episode did not show response to the adenosine treatment, but responded to digoxin and amiodarone therapy. Author comment: "Cardiorespiratory monitoring during IVIG infusion can be recommended because of the possibility of this potentially lifethreatening adverse effect [of supraventricular tachycardia]." Tufekci S, et al. Cardiac rhythm abnormalities during intravenous immunoglobulin G(IVIG) infusion in two newborn infants: coincidence or association? Clinical Case Reports 3: 731-734, No. 9, Sep 2015. Available from: URL: http:// doi.org/10.1002/ccr3.329 - Turkey 803283900 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Immune globulin

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
Free
1 page
Loading next page...
1 Page
 
/lp/springer_journal/immune-globulin-cGJshsPOOS
Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-017-39100-9
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p169 - 2 Dec 2017 Supraventricular tachycardia: 2 case reports A neonate girl and a neonate boy [ages at the time of reactions onsets not stated] were described, who developed supraventricular tachycardia (SVT) following administration of immune globulin [dosages not stated]. Case 1: A baby girl was born at 36 weeks of gestation by spontaneous vaginal delivery to a 30-year-old woman. At the th 6 postnatal hour, the baby girl’s bilirubin level was 2.8 mg/dL corresponding to a pathologic rate of increase. She was known to develop an immune haemolysis due to ABO incompatibility and was administered IV infusion of immune globulin to be given over 4 hours. After 75 mins of the immune globulin administration, her HR suddenly increased to 260 beats/min. The electrocardiography revealed narrow QRS SVT. She was treated with adenosine and her HR returned to normal (144/min). Case 2: A baby boy was born at 38 weeks of gestation to a 29-year-old healthy woman. After birth, his umbilical cord bilirubin level increased, corresponding to a pathologic rate of increase. Subsequently, he started receiving IV infusion of immune globulin to be given over 4 hours. Two hours later, his HR suddenly increased to 230 beats/min. The ECG revealed narrow QRS SVT. He was treated with adenosine and his HR returned to normal. However, the SVT episodes recurrent on th th the 5 and 8 days of life, which responded to adenosine th treatment. On the 9 day of his life, the SVT episode did not show response to the adenosine treatment, but responded to digoxin and amiodarone therapy. Author comment: "Cardiorespiratory monitoring during IVIG infusion can be recommended because of the possibility of this potentially lifethreatening adverse effect [of supraventricular tachycardia]." Tufekci S, et al. Cardiac rhythm abnormalities during intravenous immunoglobulin G(IVIG) infusion in two newborn infants: coincidence or association? Clinical Case Reports 3: 731-734, No. 9, Sep 2015. Available from: URL: http:// doi.org/10.1002/ccr3.329 - Turkey 803283900 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off