Ann Surg Oncol (2017) 24:2456–2464 DOI 10.1245/s10434-017-5922-3 O R I G IN AL ARTI CL E – HE PA TOBILI ARY T U M O R S Immaturity of Bile Canalicular–Ductule Networks in the Future Liver Remnant While Associating Liver Partition and Portal Vein Occlusion for Staged Hepatectomy (ALPPS) 1 1 2 1 Kenichi Matsuo, MD, PhD , Yukihiko Hiroshima, MD, PhD , Kazuto Yamazaki, MD, PhD , Kohei Kasahara, MD , 1 1 1 2 Yutaro Kikuchi, MD , Daisuke Kawaguchi, MD , Takashi Murakami, MD , Yasuo Ishida, MD, PhD , and Kuniya Tanaka, MD, PhD Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Teikyo University Chiba Medical Center, Chiba, Japan; Division of Diagnostic Pathology, Teikyo University Chiba Medical Center, Chiba, Japan ABSTRACT leaky TJs were seen more frequently in the ALPPS group Background. We studied histologic changes of bile (64.9 vs. 23.6%; p = 0.001). canalicular–ductule networks in the future liver remnant Conclusions. Regeneration of bile canalicular–ductule (FLR) while associating liver partition and portal vein networks in the FLR was poorer in ALPPS than PVE, occlusion for staged hepatectomy (ALPPS), since little is which may be associated with prolonged cholestasis fol- known about regeneration of these networks
Annals of Surgical Oncology – Springer Journals
Published: Jun 13, 2017
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