Eur J Nucl Med Mol Imaging (2017) 44:1742–1750 DOI 10.1007/s00259-017-3726-0 ORIGINAL ARTICLE Imaging children suffering from lymphoma: an evaluation of different F-FDG PET/MRI protocols compared to whole-body DW-MRI 1 2 2 3 Julian Kirchner & Cornelius Deuschl & Bernd Schweiger & Ken Herrmann & 2 1 1 2 Michael Forsting & Christian Buchbender & Gerald Antoch & Lale Umutlu Received: 23 February 2017 /Accepted: 9 May 2017 /Published online: 22 May 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract 96.5%, 97%, 96.5%, and 97% for PET/MRI and 77%, Objectives The objectives of this study were to evaluate and 96%, 96%, 78.5% and 86% for MRI-DWI. compare the diagnostic potential of different PET/MRI read- Conclusion F–FDG PET/MRI is superior to WB-DW-MRI ing protocols, entailing non-enhanced / contrast-enhanced and in staging pediatric lymphoma patients. Neither application of diffusion-weighted F–FDG PET/MR imaging and whole- contrast media nor DWI leads to a noticeable improvement of body diffusion-weighted MRI for lesion detection and deter- the diagnostic accuracy of PET/MRI. Thus, unenhanced PET/ mination of the tumor stage in pediatric lymphoma patients. MRI may play a crucial role for the diagnostic work-up of Methods A total of 28 F–FDG PET/MRI datasets were in- pediatric lymphoma patients in
European Journal of Nuclear Medicine and Molecular Imaging – Springer Journals
Published: May 22, 2017
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