Identification of the human switch alpha 2 region from a low-grade malt lymphoma

Identification of the human switch alpha 2 region from a low-grade malt lymphoma Mammalian Genome 11, 1145–1146 (2000). DOI: 10.1007/s003350010215 Incorporating Mouse Genome © Springer-Verlag New York Inc. 2000 Identification of the human switch alpha 2 region from a low-grade malt lymphoma Elena Nardini, Simona Rizzi, Sylvie Menard, Andrea Balsari Molecular Targeting Unit, Department of Experimental Oncology, National Cancer Institute, Via Venezian 1 Milan, and Institute of Pathology, University of Milan, 20133 Milan, Italy Received: 16 June 2000 / Accepted: 3 August 2000 Mucosa-Associated Lymphoid Tissue (MALT) lymphomas derive + − − − from marginal zone B-cells (typically IgM IgD ,CD5 ,CD10 ) and develop in a variety of extranodal locations, but most com- monly within the gastrointestinal tract (Harris et al. 1994; Woth- erspoon 1998). MALT lymphomas can be classified as either low or high grade and, in most cases, produce an immunoglobulin (Ig) with “M”-isotype. To obtain information on the maturational state of MALT lymphomas, we are investigating low-grade and high- Fig. 1. Southern blot analysis of grade cases for the presence of genomic rearrangements involving immunoglobulin heavy chain switch regions in one patient with low-grade the immunoglobulin heavy and chain (IgH) switch regions on Chr mucosa-associated lymphoid tissue 14q32 (Nardini et al. 2000, in preparation). lymphoma. Genomic DNA was http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Identification of the human switch alpha 2 region from a low-grade malt lymphoma

Loading next page...
 
/lp/springer_journal/identification-of-the-human-switch-alpha-2-region-from-a-low-grade-lKyKp7iMMS
Publisher
Springer-Verlag
Copyright
Copyright © 2000 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003350010215
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial