Identification of genes within the Krd deletion on mouse Chromosome 19

Identification of genes within the Krd deletion on mouse Chromosome 19 Mammalian Genome 10, 399–401 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 Identification of genes within the Krd deletion on mouse Chromosome 19 1 2 1 3 3 3 Weizhen Ji, Bruce Herron, Julie M. Jones, Nancy A. Jenkins, Debra J. Gilbert, Neal G. Copeland, 4 2 1 Richard Swank, Lorraine Flaherty, Miriam H. Meisler Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109-0618 USA Wadsworth Center, Albany, New York 12201-2002, USA Mammalian Genetics Laboratory, ABL-Basic Research Program, NCI, Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA Department of Molecular Genetics and Cell Biology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA Received: 25 August 1998 / Accepted: 24 November 1998 The Krd deletion, Del(19)TgN8052Mm, was generated by a non- Tlx1, Pitx3 and Nkx2-3. Four of these failed to be transmitted from targeted transgene insertion into the distal region of mouse Chr 19 the Krd chromosome (Table 1). The Cmoat gene encoding an ion (Keller et al. 1994). The length of the deletion was estimated to be transport protein was demonstrated to be deleted by a single- approximately 5 cM from the recombination rate of flanking mark- stranded conformational polymorphism (SSCP) assay. Mammalian Genome Springer Journals

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Copyright © 1999 by Springer-Verlag New York Inc.
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
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