We report a facile and efficient method for synthesis of substituted spiro[indoline-3,7′-pyrano[5,6-c:5,6-c′]dichromene]-2,6′,8′-trione derivatives by reaction of isatin and 4-hydroxy-2H-chromen-2-one. As far as we are aware, few methods have been reported for preparation of these compounds. The reaction proceeded smoothly when promoted by molecular iodine. Because it is a non-toxic, low cost, and readily available reagent, iodine is a green catalyst for synthesis of these spiroheterocyclic compounds. The other advantages of the procure are high yields, simple operation, atom economy, and mild reaction conditions.
Research on Chemical Intermediates – Springer Journals
Published: May 22, 2014
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